Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | SPR | P35270 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 5/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.48 |
| ▸ | PANK3 | Q9H999 | 6/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18701863 | 0.86 | CHRM1 (0.52) | CHRM1SPRDPP4DPP8DPP9 | |
| SCHEMBL3452836 | 0.83 | DPP4 (0.53) | DPP4DPP8DPP9DPP7PANK3 | |
| SCHEMBL25308881 | 0.82 | RET (0.56) | CHRM1SPRPANK3CHRM2GPR119 | |
| SCHEMBL26576076 | 0.82 | RET (0.56) | CHRM1SPRPANK3CHRM2GPR119 | |
| SCHEMBL30510786 | 0.82 | RET (0.56) | CHRM1SPRPANK3CHRM2GPR119 | |
| SCHEMBL30859896 | 0.81 | CHRM1 (0.56) | CHRM1SPRDPP4DPP8DPP9 | |
| SCHEMBL21853958 | 0.80 | PANK3 (0.47) | DPP4DPP8DPP9DPP7PANK3 | |
| SCHEMBL23322753 | 0.80 | GPR119 (0.45) | CHRM1SPRDPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL30859838 | 0.80 | CHRM1 (0.55) | CHRM1SPRDPP4DPP8DPP9 | |
| SCHEMBL21526390 | 0.80 | HDAC1 (0.44) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073133-A1 | PYRIDAZIN-3(2H)-ONE AND PYRIDIN-2(1H)-ONE PARP INHIBITOR COMPOUNDS | AZKARRA THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |
| WO-2023192989-A2 | PHTHALAZINONE COMPOUNDS AS PARP7 INHIBITORS | AZKARRA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |