SCHEMBL26125331

SCHEMBL26125331

CC(=O)O[C@H]1[C@H](n2ccc(NC(=O)c3ccccc3)nc2=O)O[C@](C)(COCc2ccccc2)[C@H]1OCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.45
ABL1 P00519 1/20 0.45
RIN1 Q13671 1/20 0.45
P2RY6 Q15077 8/20 0.43
P2RY14 Q15391 2/20 0.43
NT5E P21589 1/20 0.43
ST6GAL1 P15907 4/20 0.37
P2RY2 P41231 4/20 0.36
P2RY4 P51582 4/20 0.36
PTGER1 P34995 1/20 0.36
PTPN2 P17706 1/20 0.36
PTPN1 P18031 1/20 0.36
USP30 Q70CQ3 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26125336 1.00 POLB (0.45) POLBABL1RIN1P2RY6P2RY14
SCHEMBL26113415 0.90 POLB (0.42) POLBABL1RIN1P2RY6P2RY14
SCHEMBL26119053 0.89 P2RY6 (0.49) POLBABL1RIN1P2RY6P2RY14
SCHEMBL26124477 0.89 P2RY6 (0.49) POLBABL1RIN1P2RY6P2RY14
SCHEMBL1096958 0.88 P2RY6 (0.42) POLBABL1RIN1P2RY6P2RY14
SCHEMBL26122705 0.88 P2RY6 (0.42) POLBABL1RIN1P2RY6P2RY14
SCHEMBL26122701 0.88 P2RY6 (0.42) POLBABL1RIN1P2RY6P2RY14
SCHEMBL26122578 0.88 ABL1 (0.43) POLBABL1RIN1P2RY6P2RY14
SCHEMBL26123372 0.86 P2RY6 (0.37) POLBP2RY6P2RY14NT5EPTPN2
SCHEMBL26124617 0.86 P2RY6 (0.37) POLBP2RY6P2RY14NT5EPTPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215039-A1 NUCLEOSIDES FOR TREATING CANCER PRIMEFOUR THERAPEUTICS INC (US) 2025-07-03 US disclosed
WO-2023192499-A1 NUCLEOSIDES FOR TREATING CANCER PRIMEFOUR THERAPEUTICS, INC. (US) 2023-10-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215039-A1 NUCLEOSIDES FOR TREATING CANCER UNG, OGG1, NTPCR POLB 43/4885ABL1 3035/4885RIN1 3525/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.