Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UMPS | P11172 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.34 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.32 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.32 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.30 |
| ▸ | MTOR | P42345 | 2/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26127288 | 0.85 | UMPS (0.35) | UMPSSLC29A1SLC28A1SLC28A2SLC28A3 | |
| SCHEMBL28552184 | 0.79 | UMPS (0.34) | UMPSSLC29A1 | |
| SCHEMBL26129030 | 0.78 | UMPS (0.33) | UMPSSLC29A1 | |
| SCHEMBL9201080 | 0.73 | SLC28A1 (0.60) | SLC29A1SLC28A1SLC28A2SLC28A3 | |
| SCHEMBL21782461 | 0.73 | SLC28A1 (0.60) | SLC29A1SLC28A1SLC28A2SLC28A3 | |
| SCHEMBL24539202 | 0.73 | SLC28A1 (0.60) | SLC29A1SLC28A1SLC28A2SLC28A3 | |
| SCHEMBL2056844 | 0.73 | SLC28A1 (0.60) | SLC29A1SLC28A1SLC28A2SLC28A3 | |
| SCHEMBL21423092 | 0.73 | SLC28A1 (0.60) | SLC29A1SLC28A1SLC28A2SLC28A3 | |
| SCHEMBL12150756 | 0.73 | SLC28A1 (0.60) | SLC29A1SLC28A1SLC28A2SLC28A3 | |
| SCHEMBL1145390 | 0.73 | SLC28A1 (0.60) | SLC29A1SLC28A1SLC28A2SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112672764-A | Conjugates | 格莱科斯生物医药公司 | 2021-04-16 | — | — | CN | claimed |
| WO-2023197015-A1 | COMPOSITIONS AND ANALYSIS OF DEPHOSPHORYLATED OLIGORIBONUCLEOTIDES | NEW ENGLAND BIOLABS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |
| CN-112672764-A | Conjugates | 格莱科斯生物医药公司 | 2021-04-16 | — | — | CN | disclosed |