Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.45 |
| ▸ | HTR1A | P08908 | 11/20 | 0.44 |
| ▸ | HTR7 | P34969 | 11/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26223783 | 0.76 | DPP4 (0.48) | DPP4HTR1AHTR7ACE | |
| SCHEMBL19111008 | 0.76 | DPP4 (0.48) | DPP4HTR1AHTR7ACE | |
| SCHEMBL30874915 | 0.76 | DPP4 (0.45) | DPP4HTR1AHTR7ACE | |
| SCHEMBL29540069 | 0.69 | DPP4 (0.53) | DPP4HTR1AHTR7ACE | |
| SCHEMBL14463150 | 0.69 | DPP4 (0.51) | DPP4HTR1AHTR7ACE | |
| SCHEMBL30874974 | 0.68 | DPP4 (0.44) | DPP4HTR1AHTR7ACE | |
| SCHEMBL30874846 | 0.68 | DPP4 (0.47) | DPP4HTR1AHTR7 | |
| SCHEMBL12863842 | 0.68 | SMN1; SMN2 (0.47) | DPP4HTR1AHTR7ACE | |
| SCHEMBL10884099 | 0.68 | DPP4 (0.54) | DPP4HTR1AHTR7ACE | |
| SCHEMBL13954202 | 0.68 | DPP4 (0.51) | DPP4HTR1AHTR7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220425-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023069514-A2 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING ITK VIA UBIQUITIN PROTEOSOME PATHWAY | NURIX THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |