SCHEMBL26134875

SCHEMBL26134875

CC(C)n1ccc(-c2cc3ncccc3c(OC[C@@H]3CNCC(C)(C)O3)n2)c1

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SYK P43405 20/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30613650 1.00 SYK (0.45) SYK
SCHEMBL30613639 0.91 SYK (0.44) SYK
SCHEMBL26136235 0.91 SYK (0.44) SYK
SCHEMBL30613728 0.89 SYK (0.47) SYK
SCHEMBL30613646 0.88 SYK (0.47) SYK
SCHEMBL31676288 0.87 SYK (0.45) SYK
SCHEMBL31676078 0.86 SYK (0.43) SYK
SCHEMBL31676146 0.86 SYK (0.44) SYK
SCHEMBL31676320 0.86 SYK (0.44) SYK
SCHEMBL31676404 0.85 SYK (0.44) SYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023193054-A1 SPLEEN TYROSINE KINASE INHIBITORS UNIQUEST PTY LTD (AU) 2023-10-12 — — WO disclosed
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