SCHEMBL26136235

SCHEMBL26136235

CC(C)n1ccc(-c2cc3ncccc3c(OC[C@@H]3CNCC4(CC4)O3)n2)c1

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SYK P43405 20/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30613639 1.00 SYK (0.44) SYK
SCHEMBL30613650 0.91 SYK (0.45) SYK
SCHEMBL26134875 0.91 SYK (0.45) SYK
SCHEMBL31676440 0.89 SYK (0.46) SYK
SCHEMBL31676498 0.87 SYK (0.44) SYK
SCHEMBL31676418 0.86 SYK (0.44) SYK
SCHEMBL31676429 0.85 SYK (0.45) SYK
SCHEMBL31676015 0.85 SYK (0.45) SYK
SCHEMBL31676145 0.84 SYK (0.51) SYK
SCHEMBL30613622 0.84 SYK (0.46) SYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023193054-A1 SPLEEN TYROSINE KINASE INHIBITORS UNIQUEST PTY LTD (AU) 2023-10-12 — — WO disclosed
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