Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | APOL1 | O14791 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26129646 | 0.86 | GCGR (0.46) | FFAR1PPARG | |
| SCHEMBL30613272 | 0.79 | APOL1 (0.64) | FFAR1APOL1FFAR4PPARGPPARA | |
| SCHEMBL4596931 | 0.75 | FFAR4 (0.49) | FFAR1FFAR4PPARGPPARAPSEN1 | |
| SCHEMBL4007916 | 0.75 | FFAR1 (0.58) | FFAR1FFAR4PTGDR2 | |
| SCHEMBL3333875 | 0.74 | NR1H4 (0.46) | FFAR1FFAR4PSEN1PSEN2APH1B | |
| SCHEMBL26135029 | 0.74 | APOL1 (0.80) | APOL1 | |
| SCHEMBL26583923 | 0.73 | CDC7 (0.51) | APOL1 | |
| SCHEMBL7242930 | 0.73 | PPARG (0.50) | PPARG | |
| SCHEMBL31750436 | 0.72 | FFAR1 (0.54) | FFAR1FFAR4PTGDR2 | |
| Hydrochloric Acid SCHEMBL34474962 | 0.71 | FFAR1 (0.53) | FFAR1FFAR4PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023194895-A1 | PYRROL DERIVATIVES AS INHIBITORS OF APOLIPOPROTEIN L-1 | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-10-12 | — | — | WO | disclosed |