Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.45 |
| ▸ | TUBB | P07437 | 2/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26129617 | 0.87 | GCGR (0.51) | CYP4F2CYP4A11MAPTPDE3BPDE3A | |
| SCHEMBL5371838 | 0.75 | CYP4F2 (0.54) | CYP4F2CYP4A11PTPN1MAPTALDH1A1 | |
| SCHEMBL26136119 | 0.75 | PTPN1 (0.47) | CYP4F2CYP4A11PTPN1MAPTPDE3B | |
| SCHEMBL3419311 | 0.75 | CYP4F2 (0.49) | CYP4F2CYP4A11PTPN1TUBB4ATUBB | |
| SCHEMBL69660 | 0.75 | CYP4F2 (0.86) | CYP4F2CYP4A11PTPN1MAPTALDH1A1 | |
| SCHEMBL6282888 | 0.75 | CYP4F2 (0.69) | CYP4F2CYP4A11PTPN1ALDH1A1GAA | |
| SCHEMBL9394814 | 0.74 | CYP4F2 (0.69) | CYP4F2CYP4A11PTPN1MAPTALDH1A1 | |
| SCHEMBL28010240 | 0.74 | NPC1 (0.44) | GCGRMEN1KMT2A | |
| SCHEMBL1501837 | 0.74 | MAPT (0.54) | CYP4F2CYP4A11PTPN1MAPTALDH1A1 | |
| SCHEMBL2536319 | 0.73 | CYP4F2 (0.55) | CYP4F2CYP4A11PTPN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023194895-A1 | PYRROL DERIVATIVES AS INHIBITORS OF APOLIPOPROTEIN L-1 | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-10-12 | — | — | WO | disclosed |
| WO-2023194895-A1 | PYRROL DERIVATIVES AS INHIBITORS OF APOLIPOPROTEIN L-1 | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-10-12 | — | — | WO | disclosed |