Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | UGCG | Q16739 | 2/20 | 0.35 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | GYPA | P02724 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26135449 | 1.00 | TSHR (0.38) | TSHRPDE4DIDO1GRM2GRM3 | |
| SCHEMBL6872623 | 0.88 | BCHE (0.39) | TSHRPDE4DIDO1GRM2GRM3 | |
| SCHEMBL6872618 | 0.88 | BCHE (0.39) | TSHRPDE4DIDO1GRM2GRM3 | |
| SCHEMBL8718248 | 0.88 | BCHE (0.39) | TSHRPDE4DIDO1GRM2GRM3 | |
| SCHEMBL8718253 | 0.88 | BCHE (0.39) | TSHRPDE4DIDO1GRM2GRM3 | |
| SCHEMBL31693538 | 0.88 | BCHE (0.39) | TSHRPDE4DIDO1GRM2GRM3 | |
| SCHEMBL6834977 | 0.85 | BCHE (0.37) | TSHRPDE4DIDO1GRM2GRM3 | |
| SCHEMBL6834980 | 0.85 | BCHE (0.37) | TSHRPDE4DIDO1GRM2GRM3 | |
| SCHEMBL26135760 | 0.80 | GRM2 (0.35) | TSHRPDE4DIDO1GRM2GRM3 | |
| SCHEMBL26135072 | 0.79 | GRM2 (0.34) | TSHRPDE4DIDO1GRM2GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192499-A1 | NUCLEOSIDES FOR TREATING CANCER | PRIMEFOUR THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023192491-A2 | NUCLEOSIDE LINE-1 INHIBITORS | TRANSPOSON THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |