Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.35 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.35 |
| ▸ | GJB2 | P29033 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834980 | 1.00 | BCHE (0.37) | BCHEPDE4DIDO1SSTR1SSTR2 | |
| SCHEMBL23818771 | 0.86 | SSTR1 (0.36) | BCHEPDE4DIDO1SSTR1SSTR2 | |
| SCHEMBL26136642 | 0.85 | TSHR (0.38) | BCHEPDE4DIDO1GRM2GRM3 | |
| SCHEMBL26135449 | 0.85 | TSHR (0.38) | BCHEPDE4DIDO1GRM2GRM3 | |
| SCHEMBL703496 | 0.82 | BCHE (0.36) | BCHEPDE4DIDO1SSTR1SSTR2 | |
| SCHEMBL23922552 | 0.81 | BCHE (0.34) | BCHEPDE4DIDO1SSTR1SSTR2 | |
| SCHEMBL20819176 | 0.81 | BCHE (0.34) | BCHEPDE4DIDO1SSTR1SSTR2 | |
| SCHEMBL24120239 | 0.81 | BCHE (0.34) | BCHEPDE4DIDO1SSTR1SSTR2 | |
| SCHEMBL16698760 | 0.81 | BCHE (0.39) | BCHEPDE4DIDO1SSTR1SSTR2 | |
| SCHEMBL26626297 | 0.81 | LGALS8 (0.37) | BCHEPDE4DIDO1SSTR1SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229840-A1 | Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase | ISIS PHARMACEUTICALS, INC. | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229840-A1 | Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase | NSUN2, NSUN3, POLRMT | BCHE 2685/4885PDE4D 1080/4885IDO1 1047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.