SCHEMBL26144159

SCHEMBL26144159

C=C(C)C(=O)Oc1ccc(-c2ccc(-c3ccc(OC(=O)C(=C)C)c(F)c3)cc2F)c(F)c1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.40
KMT2A Q03164 2/20 0.38
ATM Q13315 1/20 0.38
BACE1 P56817 1/20 0.35
APP P05067 1/20 0.35
CYP2C19 P33261 1/20 0.35
FFAR4 Q5NUL3 8/20 0.34
CFD P00746 1/20 0.34
ERN1 O75460 2/20 0.34
FFAR1 O14842 2/20 0.34
PPARD Q03181 2/20 0.34
TDP2 O95551 1/20 0.34
ABCB1 P08183 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1098577 0.95 ELANE (0.40) ELANEKMT2AATMBACE1APP
SCHEMBL26144157 0.95 ELANE (0.40) ELANEKMT2AATMBACE1APP
SCHEMBL26144171 0.94 ELANE (0.36) ELANEKMT2AATMBACE1APP
SCHEMBL26144161 0.92 ELANE (0.37) ELANEKMT2AATMBACE1APP
SCHEMBL26144166 0.91 ELANE (0.38) ELANEKMT2AATMBACE1APP
SCHEMBL26144160 0.90 ELANE (0.43) ELANEKMT2AATMAPPCYP2C19
SCHEMBL26144315 0.90 ERN1 (0.41) ELANEKMT2AATMBACE1APP
SCHEMBL24440902 0.90 BACE1 (0.40) ELANEKMT2AATMBACE1APP
SCHEMBL26144212 0.89 ELANE (0.35) ELANEKMT2AATMBACE1APP
SCHEMBL21483461 0.89 ELANE (0.40) ELANEKMT2AATMBACE1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230142277-A1 POLYMERIZABLE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2023-05-11 US disclosed