SCHEMBL26144166

SCHEMBL26144166

C=C(C)C(=O)Oc1ccc(-c2ccc(-c3ccc(OC(=O)C(=C)C)c(C)c3)cc2F)c(F)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.38
FFAR4 Q5NUL3 4/20 0.36
FFAR1 O14842 1/20 0.36
KMT2A Q03164 1/20 0.36
ATM Q13315 1/20 0.36
AKR1C3 P42330 2/20 0.34
AKR1C2 P52895 2/20 0.34
PRKAB2 O43741 1/20 0.34
PRKAG1 P54619 1/20 0.34
PRKAA2 P54646 1/20 0.34
PRKAA1 Q13131 1/20 0.34
PRKAG3 Q9UGI9 1/20 0.34
PRKAG2 Q9UGJ0 1/20 0.34
PRKAB1 Q9Y478 1/20 0.34
PTGS2 P35354 4/20 0.33
CYP2C19 P33261 2/20 0.33
BACE1 P56817 1/20 0.33
APP P05067 1/20 0.33
DHODH Q02127 2/20 0.33
PTGS1 P23219 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26144178 0.96 ELANE (0.37) ELANEFFAR4FFAR1KMT2AATM
SCHEMBL26144176 0.95 ELANE (0.36) ELANEFFAR4FFAR1KMT2AATM
SCHEMBL26144167 0.95 AKR1C3 (0.39) ELANEFFAR4FFAR1KMT2AATM
SCHEMBL22219351 0.94 ELANE (0.39) ELANEFFAR4FFAR1KMT2AATM
SCHEMBL26144171 0.93 ELANE (0.36) ELANEFFAR4FFAR1KMT2AATM
SCHEMBL26044728 0.93 ELANE (0.41) ELANEFFAR4FFAR1KMT2AATM
SCHEMBL26144177 0.91 FFAR1 (0.38) ELANEFFAR4FFAR1KMT2AATM
SCHEMBL26144159 0.91 ELANE (0.40) ELANEFFAR4FFAR1KMT2AATM
SCHEMBL26144150 0.90 AKR1C3 (0.38) ELANEFFAR4FFAR1KMT2AATM
SCHEMBL26144174 0.90 AKR1C3 (0.42) FFAR4FFAR1KMT2AAKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230142277-A1 POLYMERIZABLE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2023-05-11 US disclosed
US-20230142277-A1 POLYMERIZABLE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2023-05-11 US disclosed