Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | GPR6 | P46095 | 10/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29555 | 0.90 | GRIN1 (0.43) | GPR6CYP2D6GRIN1GRIN2B | |
| SCHEMBL13419191 | 0.82 | SYK (0.47) | CSNK2A1PDE4DGRIN1GRIN2BPTGDR2 | |
| SCHEMBL3115490 | 0.82 | GPR6 (0.41) | GPR6CYP2D6GRIN1GRIN2B | |
| SCHEMBL622131 | 0.82 | CSNK2A1 (0.43) | CSNK2A1PDE4DPDE4AMCHR1 | |
| SCHEMBL941030 | 0.82 | SLC6A2 (0.58) | — | |
| SCHEMBL24439649 | 0.82 | NPY1R (0.49) | CSNK2A1PDE4DPTGDR2PDE4A | |
| SCHEMBL9538522 | 0.81 | SLC6A2 (0.56) | PDE4DPDE4AMCHR1 | |
| Hydrochloric Acid SCHEMBL2778482 | 0.81 | SLC6A2 (0.56) | — | |
| SCHEMBL22114120 | 0.80 | SYK (0.48) | CSNK2A1GPR6PDE4DGRIN1GRIN2B | |
| SCHEMBL5880750 | 0.80 | NPY1R (0.50) | CSNK2A1PDE4DPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3600312-B1 | PIPERIDINYL- AND PIPERAZINYL-SUBSTITUTED HETEROAROMATIC CARBOXAMIDES AS MODULATORS OF GPR6 | TAKEDA PHARMACEUTICALS CO (JP) | 2023-05-17 | — | — | EP | disclosed |