Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.43 |
| ▸ | GPR6 | P46095 | 11/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26144164 | 0.90 | CSNK2A1 (0.41) | GRIN1GRIN2BGPR6CYP2D6 | |
| SCHEMBL3115490 | 0.87 | GPR6 (0.41) | GRIN1GRIN2BGPR6CYP2D6 | |
| SCHEMBL941030 | 0.87 | SLC6A2 (0.58) | SLC6A2SLC6A3HTR1ASLC6A4 | |
| Hydrochloric Acid SCHEMBL2778482 | 0.86 | SLC6A2 (0.56) | SLC6A2SLC6A3HTR1ASLC6A4 | |
| SCHEMBL19262515 | 0.84 | GPR6 (0.51) | GPR6CYP2D6 | |
| SCHEMBL2299176 | 0.82 | GRIN1 (0.40) | GRIN1GRIN2BGPR6CYP2D6TRPA1 | |
| SCHEMBL14956969 | 0.82 | SLC6A4 (0.59) | SLC6A2SLC6A3HTR1ASLC6A4 | |
| SCHEMBL31471467 | 0.81 | GRIN1 (0.42) | GRIN1GRIN2BGPR6TRPA1SLC6A4 | |
| SCHEMBL31471369 | 0.81 | GRIN1 (0.48) | GRIN1GRIN2BGPR6CYP2D6TRPA1 | |
| Hydrochloric Acid SCHEMBL30357915 | 0.81 | SLC6A4 (0.57) | SLC6A2SLC6A3HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704118-B1 | AMINOIMIDAZOPYRIDAZINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2022-01-12 | — | — | EP | disclosed |
| US-9241487-B2 | Pyrimidine derivatives and use thereof as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-01-26 | — | — | US | disclosed |
| US-9198429-B2 | Heterocyclic alkanol-derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-01 | — | — | US | disclosed |
| US-9095136-B2 | 2-IODO imidazole-derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-08-04 | — | — | US | disclosed |
| EP-2609088-B1 | 5-IODO-TRIAZOLE DERIVATIVES | BAYER IP GMBH (DE) | 2015-04-29 | — | — | EP | disclosed |
| US-8969248-B2 | 5-iodotriazole derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-03 | — | — | US | disclosed |
| US-20140336232-A1 | 2-IODO IMIDAZOLE-DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-11-13 | — | — | US | disclosed |
| EP-2782904-A1 | NOVEL HETEROCYCLIC ALKANOL-DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2014-10-01 | — | — | EP | disclosed |
| US-20140274952-A1 | NOVEL HETEROCYCLIC ALKANOL-DERIVATIVES | BAYER INTELLCTUAL PROPERTY GMBH (DE) | 2014-09-18 | — | — | US | disclosed |
| US-20140031373-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS PESTICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-30 | — | — | US | disclosed |
| EP-2646418-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS PESTICIDES | Bayer Intellectual Property GmbH (DE) | 2013-10-09 | — | — | EP | disclosed |
| EP-2609088-A1 | 5-IODO-TRIAZOLE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2013-07-03 | — | — | EP | disclosed |
| WO-2013076227-A1 | NOVEL HETEROCYCLIC ALKANOL-DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-30 | — | — | WO | disclosed |
| US-20120220638-A1 | 5-Iodotriazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-08-30 | — | — | US | disclosed |
| WO-2012072547-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-07 | — | — | WO | disclosed |
| WO-2012025506-A1 | 5-IODO-TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336232-A1 | 2-IODO IMIDAZOLE-DERIVATIVES | CIP2A, ING2, AZI2 | GRIN1 2910/4885GRIN2B 3113/4885GPR6 4586/4885 |
| US-20140031373-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS PESTICIDES | TYMP, TYMS, UMPS | GRIN1 2890/4885GRIN2B 3096/4885GPR6 3682/4885 |
| US-20120220638-A1 | 5-Iodotriazole derivatives | INMT, IGFBP5, HDHD5 | GRIN1 2132/4885GRIN2B 2403/4885GPR6 4678/4885 |
| US-20140274952-A1 | NOVEL HETEROCYCLIC ALKANOL-DERIVATIVES | ERG28, CBR3, MYB | GRIN1 4072/4885GRIN2B 4333/4885GPR6 4173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.