Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20576900 | 0.83 | JAK2 (0.36) | JAK2BTK | |
| SCHEMBL20577313 | 0.83 | JAK2 (0.37) | JAK2BTK | |
| SCHEMBL24595249 | 0.77 | LPL (0.33) | — | |
| SCHEMBL30484203 | 0.77 | LPL (0.33) | — | |
| SCHEMBL2317559 | 0.76 | CFB (0.33) | JAK2BTK | |
| SCHEMBL20577340 | 0.75 | LPL (0.34) | JAK2BTK | |
| SCHEMBL21725713 | 0.73 | TNF (0.37) | JAK2BTK | |
| SCHEMBL31527566 | 0.73 | LPL (0.31) | JAK2BTK | |
| SCHEMBL15186948 | 0.72 | LPL (0.33) | — | |
| SCHEMBL12926609 | 0.72 | CSF1R (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151002-A1 | 6-5 FUSED RINGS AS C5a INHIBITORS | CHEMOCENTRYX, INC. | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151002-A1 | 6-5 FUSED RINGS AS C5a INHIBITORS | C5AR1, C5AR2, C3AR1 | JAK2 1230/4885BTK 323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.