Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999550 | 0.78 | SYK (0.39) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL30180668 | 0.78 | SYK (0.39) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL24003990 | 0.78 | MAPT (0.35) | MAPTDNMT1RAD52POLBTSHR | |
| SCHEMBL24003973 | 0.78 | MAPT (0.35) | MAPTDNMT1RAD52POLBTSHR | |
| SCHEMBL23999351 | 0.78 | MAPT (0.35) | MAPTDNMT1RAD52POLBTSHR | |
| SCHEMBL26323174 | 0.76 | MAPT (0.36) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL26323315 | 0.75 | CBFB (0.34) | POLBSMN1; SMN2HSD17B10 | |
| SCHEMBL24003965 | 0.74 | PDPK1 (0.41) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL30180421 | 0.74 | PDPK1 (0.41) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL23999947 | 0.74 | PDPK1 (0.41) | MAPTPOLBTSHRMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |