Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 16/20 | 0.58 |
| ▸ | FYN | P06241 | 12/20 | 0.58 |
| ▸ | ABL1 | P00519 | 11/20 | 0.58 |
| ▸ | YES1 | P07947 | 9/20 | 0.58 |
| ▸ | FGR | P09769 | 9/20 | 0.58 |
| ▸ | LYN | P07948 | 8/20 | 0.58 |
| ▸ | FRK | P42685 | 7/20 | 0.58 |
| ▸ | LCK | P06239 | 7/20 | 0.58 |
| ▸ | RET | P07949 | 5/20 | 0.58 |
| ▸ | BLK | P51451 | 8/20 | 0.50 |
| ▸ | PTK6 | Q13882 | 9/20 | 0.48 |
| ▸ | HCK | P08631 | 7/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18250080 | 0.92 | SRC (0.68) | SRCFYNABL1YES1FGR | |
| SCHEMBL18258360 | 0.86 | SRC (0.69) | SRCFYNABL1YES1FGR | |
| SCHEMBL18258364 | 0.83 | ABL1 (0.51) | SRCFYNABL1YES1FGR | |
| SCHEMBL25030582 | 0.83 | SRC (0.49) | SRCFYNABL1YES1FGR | |
| SCHEMBL18258356 | 0.82 | SRC (0.64) | SRCFYNABL1YES1FGR | |
| SCHEMBL18250081 | 0.82 | SRC (0.53) | SRCFYNABL1YES1FGR | |
| SCHEMBL25030580 | 0.82 | SRC (0.59) | SRCFYNABL1YES1FGR | |
| SCHEMBL18258367 | 0.81 | ABL1 (0.49) | SRCFYNABL1YES1FGR | |
| SCHEMBL26148254 | 0.81 | SRC (0.74) | SRCFYNABL1YES1FGR | |
| SCHEMBL25033277 | 0.81 | SRC (0.47) | SRCFYNABL1YES1FGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083373-A1 | COMPOUND USED AS SRC INHIBITOR | 微境生物医药科技(上海)有限公司 | 2023-05-19 | — | — | WO | disclosed |