Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 13/20 | 0.49 |
| ▸ | FYN | P06241 | 9/20 | 0.49 |
| ▸ | ABL1 | P00519 | 8/20 | 0.49 |
| ▸ | YES1 | P07947 | 7/20 | 0.49 |
| ▸ | FGR | P09769 | 7/20 | 0.49 |
| ▸ | FRK | P42685 | 7/20 | 0.49 |
| ▸ | LYN | P07948 | 6/20 | 0.49 |
| ▸ | RET | P07949 | 5/20 | 0.49 |
| ▸ | LCK | P06239 | 5/20 | 0.49 |
| ▸ | BLK | P51451 | 6/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | INSR | P06213 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | ROS1 | P08922 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25033277 | 0.88 | SRC (0.47) | SRCFYNABL1YES1FGR | |
| SCHEMBL18258364 | 0.84 | ABL1 (0.51) | SRCFYNABL1YES1FGR | |
| SCHEMBL18250080 | 0.84 | SRC (0.68) | SRCFYNABL1YES1FGR | |
| SCHEMBL26148542 | 0.83 | SRC (0.58) | SRCFYNABL1YES1FGR | |
| SCHEMBL18258356 | 0.83 | SRC (0.64) | SRCFYNABL1YES1FGR | |
| SCHEMBL18258360 | 0.82 | SRC (0.69) | SRCFYNABL1YES1FGR | |
| SCHEMBL18258367 | 0.82 | ABL1 (0.49) | SRCFYNABL1YES1FGR | |
| SCHEMBL18250085 | 0.81 | SRC (0.50) | SRCFYNABL1YES1FGR | |
| SCHEMBL28472880 | 0.78 | FGFR2 (0.47) | SRCFYNABL1YES1FGR | |
| SCHEMBL14268420 | 0.77 | KDR (0.70) | SRCFYNABL1RETLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4384518-B1 | TYROSINE KINASE INHIBITORS | UNIV COURT UNIV OF EDINBURGH (GB) | 2025-12-17 | — | — | EP | disclosed |
| US-20250092046-A1 | TYROSINE KINASE INHIBITORS | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2025-03-20 | — | — | US | disclosed |
| CN-117957229-A | Tyrosine kinase inhibitors | 爱丁堡大学理事会 | 2024-04-30 | — | — | CN | disclosed |
| WO-2023017264-A1 | TYROSINE KINASE INHIBITORS | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2023-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250092046-A1 | TYROSINE KINASE INHIBITORS | ABL1, ALK, TYRO3 | SRC 27/4885FYN 107/4885ABL1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.