Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21372157 | 0.97 | GBA1 (0.35) | GBA1EPHX1ADH1BADH1CADH1A | |
| SCHEMBL29080637 | 0.89 | EPHX1 (0.35) | GBA1EPHX1ADH1BADH1CADH1A | |
| SCHEMBL29080638 | 0.81 | — | — | |
| SCHEMBL24009122 | 0.80 | SLC6A1 (0.33) | GBA1 | |
| SCHEMBL24393336 | 0.73 | CHRM2 (0.36) | EPHX1ADH1BADH1CADH1AADH4 | |
| SCHEMBL18899204 | 0.70 | EPHX1 (0.31) | EPHX1 | |
| SCHEMBL779637 | 0.69 | SLC2A1 (0.34) | GBA1SLC2A1 | |
| SCHEMBL8976389 | 0.69 | EPHX1 (0.35) | EPHX1ADH1BADH1CADH1AADH4 | |
| SCHEMBL27985770 | 0.69 | EPHX1 (0.31) | EPHX1ADH1BADH1CADH1AADH4 | |
| SCHEMBL24009077 | 0.69 | SLC6A1 (0.35) | GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091957-A1 | PEPTIDE CONJUGATES OF PEPTIDIC TUBULIN INHIBITORS AS THERAPEUTICS | CYBREXA 4, INC. (US) | 2023-05-25 | — | — | WO | disclosed |