Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.58 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.54 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.54 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.47 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.46 |
| ▸ | PI4KA | P42356 | 1/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 2/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3754419 | 0.89 | CYP2A6 (0.68) | CYP2A6MKNK1MKNK2HSD17B1HSD17B2 | |
| SCHEMBL31174412 | 0.89 | CYP2A6 (0.68) | CYP2A6MKNK1MKNK2HSD17B1HSD17B2 | |
| SCHEMBL12497850 | 0.83 | MKNK1 (0.59) | CYP2A6MKNK1MKNK2HSD17B1HSD17B2 | |
| SCHEMBL13968126 | 0.83 | FYN (0.67) | PIK3CAPIK3CDPIK3CBPIK3CGFYN | |
| SCHEMBL676678 | 0.82 | HPGDS (0.56) | PIK3CAPDE10APIK3CDPIK3CBPIK3CG | |
| SCHEMBL6291372 | 0.82 | MKNK1 (0.57) | CYP2A6MKNK1MKNK2HSD17B1HSD17B2 | |
| SCHEMBL14970129 | 0.81 | CYP2A6 (0.49) | CYP2A6MKNK1MKNK2HSD17B1HSD17B2 | |
| SCHEMBL13173483 | 0.80 | PIK3CD (0.49) | CYP2A6MKNK1MKNK2PIK3CAPDE10A | |
| SCHEMBL2155503 | 0.80 | MKNK1 (0.56) | CYP2A6MKNK1MKNK2HSD17B1HSD17B2 | |
| SCHEMBL14970135 | 0.80 | DYRK1A (0.62) | CYP2A6MKNK1MKNK2HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785445-B2 | 7-phenoxychroman carboxylic acid derivatives | ARRAY BIOPHARMA INC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-20120101103-A1 | 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC. (US) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101103-A1 | 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | PTGDR2, PTGDR, HRH2 | CYP2A6 225/4885MKNK1 4492/4885MKNK2 4263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.