Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 11/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | SELL | P14151 | 3/20 | 0.46 |
| ▸ | SELE | P16581 | 3/20 | 0.46 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GALK1 | P51570 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19440344 | 1.00 | SELP (0.51) | SELPAPPSELLSELESYNJ2 | |
| SCHEMBL2627817 | 1.00 | SELP (0.51) | SELPAPPSELLSELESYNJ2 | |
| SCHEMBL14401342 | 1.00 | SELP (0.51) | SELPAPPSELLSELESYNJ2 | |
| SCHEMBL2615735 | 1.00 | SELP (0.51) | SELPAPPSELLSELESYNJ2 | |
| SCHEMBL12738925 | 1.00 | SELP (0.51) | SELPAPPSELLSELESYNJ2 | |
| SCHEMBL16875709 | 1.00 | SELP (0.51) | SELPAPPSELLSELESYNJ2 | |
| SCHEMBL2615749 | 1.00 | SELP (0.51) | SELPAPPSELLSELESYNJ2 | |
| SCHEMBL15603823 | 1.00 | SELP (0.51) | SELPAPPSELLSELESYNJ2 | |
| SCHEMBL2615734 | 1.00 | SELP (0.51) | SELPAPPSELLSELESYNJ2 | |
| SCHEMBL31533677 | 1.00 | SELP (0.51) | SELPAPPSELLSELESYNJ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139809-B2 | Bacterial vaccines with cell wall-associated ceramide-like glycolipids and uses thereof | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2015-09-22 | — | — | US | disclosed |
| US-9139809-B2 | Bacterial vaccines with cell wall-associated ceramide-like glycolipids and uses thereof | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2015-09-22 | — | — | US | disclosed |
| US-20140186378-A1 | GLYCOLIPIDS AND ANALOGUES THEREOF AS ANTIGENS FOR NKT CELLS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2014-07-03 | — | — | US | disclosed |
| US-20140186378-A1 | GLYCOLIPIDS AND ANALOGUES THEREOF AS ANTIGENS FOR NKT CELLS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2014-07-03 | — | — | US | disclosed |
| US-8586051-B2 | Glycolipids and analogues thereof as antigens for NKT cells | THE ROCKEFELLER UNIVERSITY (US) | 2013-11-19 | — | — | US | disclosed |
| US-20120258142-A1 | GLYCOLIPIDS AND ANALOGUES THEREOF AS ANTIGENS FOR NKT CELLS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-10-11 | — | — | US | disclosed |
| US-20120258142-A1 | GLYCOLIPIDS AND ANALOGUES THEREOF AS ANTIGENS FOR NKT CELLS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-10-11 | — | — | US | disclosed |
| US-8163290-B2 | Glycolipids and analogues thereof as antigens for NKT cells | THE ROCKEFELLER UNIVERSITY (US) | 2012-04-24 | — | — | US | disclosed |
| US-8163290-B2 | Glycolipids and analogues thereof as antigens for NKT cells | THE ROCKEFELLER UNIVERSITY (US) | 2012-04-24 | — | — | US | disclosed |
| US-20110086053-A1 | Glycolipids And Analogues Thereof As Antigens For NKT Cells | THE ROCKEFELLER UNIVERSITY (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086053-A1 | Glycolipids And Analogues Thereof As Antigens For NKT Cells | THE ROCKEFELLER UNIVERSITY (US) | 2011-04-14 | — | — | US | disclosed |
| US-7923013-B2 | Glycolipids and analogues thereof as antigens for NKT cells | THE ROCKEFELLER UNIVERSITY (US) | 2011-04-12 | — | — | US | disclosed |
| US-7923013-B2 | Glycolipids and analogues thereof as antigens for NKT cells | THE ROCKEFELLER UNIVERSITY (US) | 2011-04-12 | — | — | US | disclosed |
| US-20100183549-A1 | BACTERIAL VACCINES WITH CELL WALL-ASSOCIATED CERAMIDE-LIKE GLYCOLIPIDS AND USES THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2010-07-22 | — | — | US | disclosed |
| US-20090233875-A1 | GLYCOLIPIDS AND ANALOGUES THEREOF AS ANTIGENS FOR NK T CELLS | THE ROCKEFELLER UNIVERSITY (US) | 2009-09-17 | — | — | US | disclosed |
| US-7534434-B2 | Glycolipids and analogues thereof as antigens for NK T cells | THE ROCKEFELLER UNIVERSITY (US) | 2009-05-19 | — | — | US | disclosed |
| US-20090117089-A1 | GLYCOLIPIDS AND ANALOGUES THEREOF AS ANTIGENS FOR NK T CELLS | THE ROCKEFELLER UNIVERSITY (US) | 2009-05-07 | — | — | US | disclosed |
| WO-2008128062-A1 | GLYCOLIPIDS AND ANALOGUES THEREOF AS ANTIGENS FOR NK T CELLS | THE ROCKEFELLER UNIVERSITY (US) | 2008-10-23 | — | — | WO | disclosed |
| US-20070238871-A1 | Glycolipids And Analogues Thereof As Antigens For NKT Cells | THE ROCKEFELLER UNIVERSITY (US) | 2007-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120258142-A1 | GLYCOLIPIDS AND ANALOGUES THEREOF AS ANTIGENS FOR NKT CELLS | CD69, KLRK1, PBK | SELP 255/4885APP 2638/4885SELL 184/4885 |
| US-20100183549-A1 | BACTERIAL VACCINES WITH CELL WALL-ASSOCIATED CERAMIDE-LIKE GLYCOLIPIDS AND USES THEREOF | SGMS1, SGMS2, SMPD3 | SELP 537/4885APP 720/4885SELL 944/4885 |
| US-20090117089-A1 | GLYCOLIPIDS AND ANALOGUES THEREOF AS ANTIGENS FOR NK T CELLS | PBK, CD69, KLRK1 | SELP 170/4885APP 3313/4885SELL 110/4885 |
| US-20110086053-A1 | Glycolipids And Analogues Thereof As Antigens For NKT Cells | CD69, KLRK1, PBK | SELP 255/4885APP 2638/4885SELL 184/4885 |
| US-20090233875-A1 | GLYCOLIPIDS AND ANALOGUES THEREOF AS ANTIGENS FOR NK T CELLS | PBK, CD69, KLRK1 | SELP 170/4885APP 3313/4885SELL 110/4885 |
| US-20140186378-A1 | GLYCOLIPIDS AND ANALOGUES THEREOF AS ANTIGENS FOR NKT CELLS | CD69, KLRK1, PBK | SELP 255/4885APP 2638/4885SELL 184/4885 |
| US-20070238871-A1 | Glycolipids And Analogues Thereof As Antigens For NKT Cells | CD69, KLRK1, PBK | SELP 255/4885APP 2638/4885SELL 184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.