SCHEMBL26157399

SCHEMBL26157399

COCCCCCCCCCN1CCC(C)CC1

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 16/20 0.56
KDM4E B2RXH2 1/20 0.54
RECQL P46063 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
ALDH1A1 P00352 1/20 0.51
LMNA P02545 1/20 0.51
KMT2A Q03164 1/20 0.51
SIGMAR1 Q99720 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26157410 1.00 HRH3 (0.56) HRH3KDM4ERECQLTDP1ALDH1A1
SCHEMBL20234910 1.00 HRH3 (0.56) HRH3KDM4ERECQLTDP1ALDH1A1
SCHEMBL26157409 1.00 HRH3 (0.56) HRH3KDM4ERECQLTDP1ALDH1A1
SCHEMBL26157397 1.00 HRH3 (0.56) HRH3KDM4ERECQLTDP1ALDH1A1
SCHEMBL26157401 1.00 HRH3 (0.56) HRH3KDM4ERECQLTDP1ALDH1A1
SCHEMBL26157408 1.00 HRH3 (0.56) HRH3KDM4ERECQLTDP1ALDH1A1
SCHEMBL20234909 0.98 KDM4E (0.55) HRH3KDM4ERECQLTDP1ALDH1A1
SCHEMBL20231628 0.93 HRH3 (0.50) HRH3KDM4ERECQLTDP1ALDH1A1
SCHEMBL12704907 0.92 SIGMAR1 (0.54) HRH3KDM4ERECQLTDP1ALDH1A1
SCHEMBL20234908 0.91 KDM4E (0.49) HRH3KDM4ERECQLTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023093728-A1 BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF 江苏先声药业有限公司 2023-06-01 WO disclosed