Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.30 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2616340 | 0.87 | TSPO (0.31) | TSPO | |
| SCHEMBL16300954 | 0.85 | TSHR (0.36) | TSHRIDH1TSPOGRIA2 | |
| SCHEMBL2616338 | 0.83 | TSPO (0.43) | IDH1TSPO | |
| SCHEMBL2616348 | 0.71 | TSPO (0.39) | TSPO | |
| SCHEMBL16300952 | 0.71 | TSPO (0.34) | TSPO | |
| SCHEMBL2616346 | 0.71 | TSPO (0.38) | TSPO | |
| SCHEMBL16300953 | 0.71 | SMN1; SMN2 (0.38) | TSHRTSPO | |
| SCHEMBL16300966 | 0.69 | TSPO (0.41) | TSPO | |
| SCHEMBL242536 | 0.68 | IDH1 (0.47) | IDH1 | |
| SCHEMBL16300951 | 0.67 | TSPO (0.48) | TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101082-A1 | VASOPRESSIN V1A ANTAGONISTS | BATT ANDRZEJ ROMAN (GB) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101082-A1 | VASOPRESSIN V1A ANTAGONISTS | AVPR1A, AVPR2, AVPR1B | TSHR 460/4885IDH1 3133/4885TSPO 1733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.