SCHEMBL26164172

SCHEMBL26164172

Nc1cccc2c1[nH]c1ccccc1c1c(-c3ccccc3)cccc1c1ccccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
PARP1 P09874 1/20 0.47
CDK4 P11802 8/20 0.45
CCND1 P24385 8/20 0.45
LIMK1 P53667 2/20 0.42
CLK4 Q9HAZ1 2/20 0.42
CDK5 Q00535 2/20 0.42
MAP4K4 O95819 1/20 0.42
CSF1R P07333 1/20 0.42
FGFR1 P11362 1/20 0.42
PDGFRA P16234 1/20 0.42
LTK P29376 1/20 0.42
KDR P35968 1/20 0.42
MAPK8 P45983 1/20 0.42
CSNK1A1 P48729 1/20 0.42
ACVR1 Q04771 1/20 0.42
TNK2 Q07912 1/20 0.42
AURKB Q96GD4 1/20 0.42
DYRK1B Q9Y463 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26164179 0.87 CDK4 (0.49) POLBTDP1PARP1CDK4CCND1
SCHEMBL26164147 0.81 PARP1 (0.56) POLBTDP1PARP1CDK4CCND1
SCHEMBL26164140 0.81 POLB (0.70) POLBTDP1PARP1LIMK1ALDH1A1
SCHEMBL7054109 0.80 GABRP (0.51) CDK4CCND1CDK5GABRPGABRD
SCHEMBL28376841 0.79 GABRP (0.47) CDK4CCND1LIMK1CLK4CDK5
SCHEMBL194195 0.79 TDP1 (0.72) POLBTDP1PARP1LIMK1ALDH1A1
SCHEMBL29352370 0.79 TDP1 (0.72) POLBTDP1PARP1LIMK1ALDH1A1
SCHEMBL29177771 0.78 POLB (0.46) POLBTDP1CDK4CCND1LIMK1
Hydrochloric Acid SCHEMBL5254930 0.77 TDP1 (0.70) POLBTDP1PARP1LIMK1ALDH1A1
Biphenyl SCHEMBL28630806 0.77 GABRP (0.60) POLBCDK4CCND1CDK5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167145-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-01 US disclosed
US-20230167145-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167145-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP POLB 2013/4885TDP1 1863/4885PARP1 2010/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.