SCHEMBL2616602

SCHEMBL2616602

Cc1cc(C)n(-c2cccc(Oc3cccc(Oc4ccccn4)c3)c2)n1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.53
ALDH1A1 P00352 2/20 0.53
GRM5 P41594 2/20 0.49
POLB P06746 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47
FFAR4 Q5NUL3 1/20 0.46
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
RAB9A P51151 2/20 0.43
NPC1 O15118 1/20 0.43
TP53 P04637 1/20 0.43
DRD1 P21728 2/20 0.40
TLR4 O00206 1/20 0.40
TLR2 O60603 1/20 0.40
LMNA P02545 1/20 0.39
GCK P35557 1/20 0.39
MGLL Q99685 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12877229 0.97 SMN1; SMN2 (0.55) SMN1; SMN2ALDH1A1GRM5POLBRXFP1
SCHEMBL2616607 0.85 SMN1; SMN2 (0.52) SMN1; SMN2ALDH1A1POLBRXFP1CASP3
SCHEMBL11990720 0.81 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1GRM5POLBRXFP1
SCHEMBL15602369 0.78 TLR4 (0.55) SMN1; SMN2ALDH1A1GRM5FFAR4TDP1
SCHEMBL22147818 0.78 SMN1; SMN2 (0.52) SMN1; SMN2ALDH1A1POLBRXFP1CASP3
SCHEMBL19620285 0.77 SMN1; SMN2 (0.43) SMN1; SMN2ALDH1A1GRM5POLBRXFP1
SCHEMBL20834862 0.77 SMN1; SMN2 (0.46) SMN1; SMN2ALDH1A1POLBRXFP1CASP3
SCHEMBL29612417 0.77 TLR4 (0.56) SMN1; SMN2ALDH1A1GRM5POLBFFAR4
SCHEMBL12129555 0.77 TLR4 (0.56) SMN1; SMN2ALDH1A1GRM5POLBFFAR4
SCHEMBL16872778 0.76 GRM5 (0.43) SMN1; SMN2ALDH1A1GRM5POLBFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2417217-B1 SYNTHESIS OF FOUR COORDINATED PLATINUM COMPLEXES AND THEIR APPLICATIONS IN LIGHT EMITTING DEVICES THEREOF ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIV (US) 2017-11-22 EP disclosed
US-9711742-B2 Four coordinated platinum and palladium complexes with geometrically distorted charge transfer state and their applications in light emitting devices ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2017-07-18 US disclosed
US-9711742-B2 Four coordinated platinum and palladium complexes with geometrically distorted charge transfer state and their applications in light emitting devices ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2017-07-18 US disclosed
US-9711742-B2 Four coordinated platinum and palladium complexes with geometrically distorted charge transfer state and their applications in light emitting devices ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2017-07-18 US disclosed
US-20170047533-A1 Four Coordinated Platinum and Palladium Complexes with Geometrically Distorted Charge Transfer State and Their Applications in Light Emitting Devices NATIONAL SCIENCE FOUNDATION 2017-02-16 US disclosed
US-20170047533-A1 Four Coordinated Platinum and Palladium Complexes with Geometrically Distorted Charge Transfer State and Their Applications in Light Emitting Devices NATIONAL SCIENCE FOUNDATION 2017-02-16 US disclosed
US-20170047533-A1 Four Coordinated Platinum and Palladium Complexes with Geometrically Distorted Charge Transfer State and Their Applications in Light Emitting Devices NATIONAL SCIENCE FOUNDATION 2017-02-16 US disclosed
US-9550801-B2 Synthesis of four coordinated platinum complexes and their applications in light emitting devices thereof ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2017-01-24 US disclosed
US-9550801-B2 Synthesis of four coordinated platinum complexes and their applications in light emitting devices thereof ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2017-01-24 US disclosed
US-9425415-B2 Four coordinated platinum and palladium complexes with geometrically distorted charge transfer state and their applications in light emitting devices ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2016-08-23 US disclosed
US-8816080-B2 Four coordinated platinum and palladium complexes with geometrically distorted charge transfer state and their applications in light emitting devices ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2014-08-26 US disclosed
US-8816080-B2 Four coordinated platinum and palladium complexes with geometrically distorted charge transfer state and their applications in light emitting devices ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2014-08-26 US disclosed
US-8816080-B2 Four coordinated platinum and palladium complexes with geometrically distorted charge transfer state and their applications in light emitting devices ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2014-08-26 US disclosed
WO-2012112853-A1 FOUR COORDINATED PLATINUM AND PALLADIUM COMPLEXES WITH GEOMETRICALLY DISTORTED CHARGE TRANSFER STATE AND THEIR APPLICATIONS IN LIGHT EMITTING DEVICES ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2012-08-23 WO disclosed
US-20120215001-A1 FOUR COORDINATED PLATINUM AND PALLADIUM COMPLEXES WITH GEOMETRICALLY DISTORTED CHARGE TRANSFER STATE AND THEIR APPLICATIONS IN LIGHT EMITTING DEVICES NATIONAL SCIENCE FOUNDATION 2012-08-23 US disclosed
US-20120215001-A1 FOUR COORDINATED PLATINUM AND PALLADIUM COMPLEXES WITH GEOMETRICALLY DISTORTED CHARGE TRANSFER STATE AND THEIR APPLICATIONS IN LIGHT EMITTING DEVICES NATIONAL SCIENCE FOUNDATION 2012-08-23 US disclosed
US-20120215001-A1 FOUR COORDINATED PLATINUM AND PALLADIUM COMPLEXES WITH GEOMETRICALLY DISTORTED CHARGE TRANSFER STATE AND THEIR APPLICATIONS IN LIGHT EMITTING DEVICES NATIONAL SCIENCE FOUNDATION 2012-08-23 US disclosed
US-20120095232-A1 SYNTHESIS OF FOUR COORDINATED PLATINUM COMPLEXES AND THEIR APPLICATIONS IN LIGHT EMITTING DEVICES THEREOF ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY 2012-04-19 US disclosed
US-20120095232-A1 SYNTHESIS OF FOUR COORDINATED PLATINUM COMPLEXES AND THEIR APPLICATIONS IN LIGHT EMITTING DEVICES THEREOF ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY 2012-04-19 US disclosed
WO-2010118026-A2 SYNTHESIS OF FOUR COORDINATED PLATINUM COMPLEXES AND THEIR APPLICATIONS IN LIGHT EMITTING DEVICES THEREOF ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2010-10-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120215001-A1 FOUR COORDINATED PLATINUM AND PALLADIUM COMPLEXES WITH GEOMETRICALLY DISTORTED CHARGE TRANSFER STATE AND THEIR APPLICATIONS IN LIGHT EMITTING DEVICES PDCD4, PDCD1LG2, PDCD1 SMN1; SMN2 3301/4885ALDH1A1 1858/4885GRM5 2088/4885
US-20170047533-A1 Four Coordinated Platinum and Palladium Complexes with Geometrically Distorted Charge Transfer State and Their Applications in Light Emitting Devices PDCD4, PDCD1LG2, PDCD1 SMN1; SMN2 3301/4885ALDH1A1 1858/4885GRM5 2088/4885
US-20120095232-A1 SYNTHESIS OF FOUR COORDINATED PLATINUM COMPLEXES AND THEIR APPLICATIONS IN LIGHT EMITTING DEVICES THEREOF ERCC4, PPOX, ERCC1 SMN1; SMN2 4153/4885ALDH1A1 2328/4885GRM5 2250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.