⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050360 | 1.00 | — | — | |
| SCHEMBL5663485 | 0.84 | ALDH1A1 (0.41) | — | |
| SCHEMBL25246818 | 0.84 | ALDH1A1 (0.48) | — | |
| SCHEMBL15609520 | 0.82 | ALDH1A1 (0.39) | — | |
| SCHEMBL23098861 | 0.82 | ALDH1A1 (0.39) | — | |
| SCHEMBL28856106 | 0.80 | — | — | |
| SCHEMBL19373024 | 0.79 | ALDH1A1 (0.41) | — | |
| SCHEMBL6142434 | 0.79 | ALDH1A1 (0.41) | — | |
| SCHEMBL18923956 | 0.79 | ALDH1A1 (0.37) | — | |
| SCHEMBL1326400 | 0.78 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9950067-B2 | Trans carotenoids, their synthesis, formulation and uses | Diffusion Pharmaceuticals, LLC (US) | 2018-04-24 | — | — | US | disclosed |
| US-20170202798-A1 | BIPOLAR TRANS CARTENOID SALTS AND THEIR USES | DIFFUSION PHARMACEUTICALS LLC (US) | 2017-07-20 | — | — | US | disclosed |
| WO-2017066633-A1 | EP4 ANTAGONISTS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2017-04-20 | — | — | WO | disclosed |
| US-9604899-B2 | Bipolar trans carotenoid salts and their uses | DIFFUSION PHARMACEUTICALS LLC (US) | 2017-03-28 | — | — | US | disclosed |
| US-20160199490-A1 | TRANS CAROTENOIDS, THEIR SYNTHESIS, FORMULATION AND USES | Diffusion Pharmaceuticals, LLC | 2016-07-14 | — | — | US | disclosed |
| US-20150333280-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-11-19 | — | — | US | disclosed |
| US-20150315243-A1 | METHODS FOR THE SYNTHESIS OF DICARBA BRIDGES IN ORGANIC COMPOUNDS | SYNGENE LTD (AU) | 2015-11-05 | — | — | US | disclosed |
| EP-1984384-B1 | Conotoxin analogues, and methods for synthesis of intramolecular dicarba bridge containing peptides | SYNGENE LTD (AU) | 2015-10-21 | — | — | EP | disclosed |
| US-9102708-B2 | Methods for the synthesis of dicarba bridges in organic compounds | SYNGENE LIMITED (AU) | 2015-08-11 | — | — | US | disclosed |
| US-8759480-B2 | Contoxin analogues and methods for synthesis of intramolecular dicarba bridge-containing peptides | SYNGENE LIMITED (AU) | 2014-06-24 | — | — | US | disclosed |
| US-20110196038-A1 | Bipolar trans carotenoid salts and their uses | DIFFUSION PHARMACEUTICALS LLC (US) | 2011-08-11 | — | — | US | disclosed |
| US-7858710-B2 | Highly organized polyolefin structures | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-12-28 | — | — | US | disclosed |
| US-7858710-B2 | Highly organized polyolefin structures | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-12-28 | — | — | US | disclosed |
| US-20100036089-A1 | Methods for the Synthesis of Dicarba Bridges in Organic Compounds | MONASH UNIVERSITY (AU) | 2010-02-11 | — | — | US | disclosed |
| US-20100022749-A1 | Contoxin Analogues and Methods for Synthesizing Same | MONASH UNIVERSITY (AU) | 2010-01-28 | — | — | US | disclosed |
| US-20090306319-A1 | Highly Organized Polyolefin Structures | UNIVERSITY OF FLORDIA RESEARCH FOUNDATION, INC. (US) | 2009-12-10 | — | — | US | disclosed |
| US-20090306319-A1 | Highly Organized Polyolefin Structures | UNIVERSITY OF FLORDIA RESEARCH FOUNDATION, INC. (US) | 2009-12-10 | — | — | US | disclosed |
| US-4806605-A | Monomers and initiators for group transfer polymerization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-02-21 | — | — | US | disclosed |
| EP-0276976-A2 | Monomers and initiators for group transfer polymerization | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-08-03 | — | — | EP | disclosed |
| US-4195184-A | Preparation of unsaturated monoesters by catalytic oxidative carbonylation of diolefins | ATLANTIC RICHFIELD COMPANY (US) | 1980-03-25 | — | — | US | disclosed |