Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26167728 | 0.94 | GAA (0.36) | GAAMAPTMAOBNR1H4ALDH1A1 | |
| SCHEMBL26167743 | 0.94 | SMN1; SMN2 (0.35) | GAAMAPTMAOBNR1H4ALDH1A1 | |
| SCHEMBL22598280 | 0.93 | GAA (0.38) | GAAMAPTMAOBALDH1A1SMPD1 | |
| SCHEMBL22598381 | 0.93 | GAA (0.38) | GAAMAPTMAOBALDH1A1SMPD1 | |
| SCHEMBL22327329 | 0.93 | GAA (0.38) | GAAMAPTMAOBALDH1A1SMPD1 | |
| SCHEMBL26068370 | 0.92 | GAA (0.37) | GAAMAPTMAOBALDH1A1SMPD1 | |
| SCHEMBL26167741 | 0.92 | GAA (0.36) | GAAMAPTMAOBNR1H4ALDH1A1 | |
| SCHEMBL22327213 | 0.89 | ALDH1A1 (0.35) | GAAMAPTMAOBALDH1A1SMPD1 | |
| SCHEMBL22327242 | 0.89 | ALDH1A1 (0.35) | GAAMAPTMAOBALDH1A1SMPD1 | |
| SCHEMBL22598408 | 0.89 | ALDH1A1 (0.35) | GAAMAPTMAOBALDH1A1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230160001-A1 | NUCLEOTIDE CLEAVABLE LINKERS WITH RIGID SPACERS AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-05-25 | — | — | US | disclosed |