Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26167803 | 0.89 | CYP1A2 (0.35) | MAP3K5HRH3CYP1A2 | |
| SCHEMBL25852783 | 0.80 | HRH3 (0.38) | MAP3K5HRH3HSP90AA1PTGER1 | |
| SCHEMBL31463165 | 0.79 | MAP3K5 (0.41) | MAP3K5HRH3OGAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL30133712 | 0.77 | MAP3K5 (0.41) | MAP3K5HRH3OGAALDH1A1MAPT | |
| SCHEMBL26167809 | 0.77 | MAP3K5 (0.41) | MAP3K5HRH3HSP90AA1PTGER1OGA | |
| SCHEMBL26167807 | 0.76 | HRH3 (0.40) | HRH3HSP90AA1PTGER1KDM4EALDH1A1 | |
| SCHEMBL26167805 | 0.76 | OGA (0.40) | MAP3K5HSP90AA1OGAMAPT | |
| SCHEMBL31463170 | 0.76 | MAP3K5 (0.41) | MAP3K5HRH3HSP90AA1OGAKDM4E | |
| SCHEMBL25091481 | 0.75 | HRH3 (0.38) | MAP3K5HRH3HSP90AA1OGA | |
| SCHEMBL16624104 | 0.72 | HRH3 (0.38) | MAP3K5HRH3PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230160001-A1 | NUCLEOTIDE CLEAVABLE LINKERS WITH RIGID SPACERS AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-05-25 | — | — | US | disclosed |