Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.40 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26167901 | 0.89 | KCNH2 (0.40) | HRH3HSP90AA1KCNH2 | |
| SCHEMBL28641279 | 0.81 | HRH3 (0.44) | HRH3MOGAT2ACACBHSP90AA1KCNH2 | |
| SCHEMBL21140748 | 0.80 | HRH3 (0.45) | HRH3MOGAT2KDM4EHSP90AA1KCNH2 | |
| SCHEMBL26122391 | 0.79 | HRH3 (0.44) | HRH3MOGAT2ACACBHSP90AA1KCNH2 | |
| SCHEMBL21482067 | 0.79 | HRH3 (0.44) | HRH3MOGAT2ACACBKDM4EALDH1A1 | |
| SCHEMBL23032967 | 0.79 | HRH3 (0.44) | HRH3MOGAT2KCNH2TLR7 | |
| SCHEMBL25091108 | 0.77 | MOGAT2 (0.43) | HRH3MOGAT2HSP90AA1KCNH2TLR7 | |
| SCHEMBL26167804 | 0.76 | MAP3K5 (0.35) | HRH3KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL26167813 | 0.76 | PTGER1 (0.44) | HRH3ACACBKDM4EALDH1A1LMNA | |
| SCHEMBL21462204 | 0.76 | HRH3 (0.48) | HRH3MOGAT2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230160001-A1 | NUCLEOTIDE CLEAVABLE LINKERS WITH RIGID SPACERS AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-05-25 | — | — | US | disclosed |