Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 8/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.53 |
| ▸ | CDK2 | P24941 | 4/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.43 |
| ▸ | CDK9 | P50750 | 3/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26174734 | 0.85 | CLK1 (0.45) | CLK1DYRK1ACDK2CCNT1CCNA2 | |
| SCHEMBL26174652 | 0.85 | JAK2 (0.50) | CLK1DYRK1ACDK2CCNT1CCNA2 | |
| SCHEMBL26174486 | 0.84 | TGFBR1 (0.53) | CLK1DYRK1ACDK2CCNT1CCNA2 | |
| SCHEMBL26175244 | 0.82 | CDK8 (0.59) | CLK1DYRK1ACDK2CCNT1CCNA2 | |
| SCHEMBL26175446 | 0.81 | CCNT1 (0.57) | CLK1DYRK1ACDK2CCNT1CCNA2 | |
| SCHEMBL26175156 | 0.81 | DYRK1A (0.53) | CLK1DYRK1ACDK2NTRK1CLK4 | |
| SCHEMBL26175521 | 0.81 | CCNT1 (0.49) | CLK1DYRK1ACDK2CCNT1CCNA2 | |
| SCHEMBL26175485 | 0.80 | CCNT1 (0.47) | CLK1DYRK1ACDK2CCNT1CCNA2 | |
| SCHEMBL26175285 | 0.79 | KIT (0.52) | CLK1DYRK1ACDK2CCNT1CCNA2 | |
| SCHEMBL26175737 | 0.77 | TGFBR1 (0.43) | CLK1DYRK1ACDK2CCNT1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192686-A1 | 1H-PYRROLO[2,3-B]PYRIDINES AND PREPARATION AND USES THEREOF | TENARX, INC. | 2023-06-22 | — | — | US | disclosed |
| US-20230192686-A1 | 1H-PYRROLO[2,3-B]PYRIDINES AND PREPARATION AND USES THEREOF | TENARX, INC. | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192686-A1 | 1H-PYRROLO[2,3-B]PYRIDINES AND PREPARATION AND USES THEREOF | DYRK1A, DYRK1B, DYRK2 | CLK1 268/4885DYRK1A 1/4885CDK2 212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.