Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | HTR1F | P30939 | 4/20 | 0.41 |
| ▸ | HTR1D | P28221 | 3/20 | 0.41 |
| ▸ | HTR1B | P28222 | 3/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 9/20 | 0.41 |
| ▸ | GSK3B | P49841 | 10/20 | 0.40 |
| ▸ | WNT1 | P04628 | 5/20 | 0.40 |
| ▸ | ABL1 | P00519 | 3/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30398345 | 1.00 | JAK1 (0.42) | JAK1HTR1AHTR1FHTR1DHTR1B | |
| SCHEMBL26176118 | 0.94 | DYRK1A (0.42) | JAK1HTR1AHTR1FHTR1DHTR1B | |
| SCHEMBL30399299 | 0.94 | DYRK1A (0.42) | JAK1HTR1AHTR1FHTR1DHTR1B | |
| SCHEMBL30398707 | 0.88 | ABL1 (0.41) | DYRK1AGSK3BWNT1ABL1 | |
| SCHEMBL26177061 | 0.88 | ABL1 (0.41) | DYRK1AGSK3BWNT1ABL1 | |
| SCHEMBL30400001 | 0.85 | JAK1 (0.41) | JAK1HTR1AHTR1FHTR1DHTR1B | |
| SCHEMBL26176120 | 0.85 | JAK1 (0.41) | JAK1HTR1AHTR1FHTR1DHTR1B | |
| SCHEMBL30400221 | 0.82 | ABL1 (0.42) | DYRK1AGSK3BWNT1ABL1 | |
| SCHEMBL26177062 | 0.82 | ABL1 (0.42) | DYRK1AGSK3BWNT1ABL1 | |
| SCHEMBL30399194 | 0.81 | DYRK1A (0.43) | JAK1HTR1AHTR1FHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192686-A1 | 1H-PYRROLO[2,3-B]PYRIDINES AND PREPARATION AND USES THEREOF | TENARX, INC. | 2023-06-22 | — | — | US | disclosed |
| US-20230192686-A1 | 1H-PYRROLO[2,3-B]PYRIDINES AND PREPARATION AND USES THEREOF | TENARX, INC. | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192686-A1 | 1H-PYRROLO[2,3-B]PYRIDINES AND PREPARATION AND USES THEREOF | DYRK1A, DYRK1B, DYRK2 | JAK1 421/4885HTR1A 1113/4885HTR1F 2085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.