Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14525541 | 0.88 | TRPV4 (0.37) | TRPV4GRM5AKR1B1USP30HTR1D | |
| SCHEMBL26178856 | 0.86 | MEN1 (0.39) | MEN1KMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL14525546 | 0.85 | TRPV4 (0.35) | TRPV4GRM5AKR1B1HTR1DHTR1B | |
| SCHEMBL14259452 | 0.79 | HTR2A (0.32) | HPGD | |
| SCHEMBL14525549 | 0.75 | TRPV4 (0.35) | TRPV4AKR1B1 | |
| SCHEMBL16233593 | 0.74 | HTR2A (0.48) | PGRKDM4EALDH1A1AR | |
| SCHEMBL21520728 | 0.72 | TRPV4 (0.45) | TRPV4CYP11B1CYP11B2KDM4EGAA | |
| SCHEMBL6651303 | 0.71 | TRPV4 (0.71) | TRPV4CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL26177017 | 0.69 | KDM1A (0.39) | AKR1B1KDM1A | |
| SCHEMBL9489932 | 0.69 | TRPV4 (0.61) | TRPV4CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107630-A2 | AMINO ALCOHOL COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |