SCHEMBL26178698

SCHEMBL26178698

CNCC1CCC(C(=O)NC(Cc2ccc3ccccc3c2)C(=O)NCCCCC(NC(=O)NC(CCC(=O)O)C(=O)O)C(=O)O)CC1

nearest known ligand 0.78

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 17/20 0.78
▸ PLG P00747 2/20 0.54
▸ PRSS1 P07477 2/20 0.54
▸ PRSS2 P07478 2/20 0.54
▸ PRSS3 P35030 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26001462 1.00 FOLH1 (0.78) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL24334720 0.96 FOLH1 (0.78) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL19296386 0.93 FOLH1 (0.77) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL29679267 0.93 FOLH1 (0.79) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL21310703 0.93 FOLH1 (0.82) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL19296389 0.93 FOLH1 (0.76) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL22883093 0.92 FOLH1 (0.75) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL26758444 0.92 FOLH1 (0.75) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL19296398 0.92 FOLH1 (0.77) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL28659047 0.92 FOLH1 (0.76) FOLH1PLGPRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023097038-A1 CLEAVABLE RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF FULL-LIFE TECHNOLOGIES U.S. INC. (US) 2023-06-01 — — WO disclosed
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