Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25230721 | 0.82 | HASPIN (0.40) | HASPINMEN1KMT2ALMNATDP1 | |
| SCHEMBL26341310 | 0.82 | HASPIN (0.40) | HASPINMEN1KMT2ALMNAHTT | |
| SCHEMBL30460844 | 0.82 | HASPIN (0.40) | HASPINMEN1KMT2ALMNATDP1 | |
| SCHEMBL30460896 | 0.78 | KMT2A (0.44) | HASPINMEN1KMT2ALMNAHTT | |
| SCHEMBL25275333 | 0.78 | KMT2A (0.44) | HASPINMEN1KMT2ALMNAHTT | |
| SCHEMBL18291265 | 0.77 | KMT2A (0.42) | PKMMEN1KMT2ALMNATDP1 | |
| SCHEMBL31164152 | 0.77 | KMT2A (0.42) | PKMMEN1KMT2ALMNATDP1 | |
| SCHEMBL27034848 | 0.76 | HASPIN (0.42) | HASPINMEN1KMT2ALMNAHTT | |
| SCHEMBL15507768 | 0.76 | HASPIN (0.42) | HASPINMEN1KMT2ALMNAHTT | |
| SCHEMBL20331427 | 0.75 | NPC1 (0.46) | HASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109959-A1 | CDK9 INHIBITOR AND USE THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-06-22 | — | — | WO | disclosed |