⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7636660 | 1.00 | ALDH1A1 (1.00) | — | |
| SCHEMBL284455 | 1.00 | ALDH1A1 (1.00) | — | |
| SCHEMBL284300 | 1.00 | ALDH1A1 (1.00) | — | |
| SCHEMBL50887 | 1.00 | ALDH1A1 (1.00) | — | |
| Dodecane SCHEMBL10526677 | 1.00 | ALDH1A1 (1.00) | — | |
| SCHEMBL2373485 | 1.00 | ALDH1A1 (1.00) | — | |
| SCHEMBL23495987 | 1.00 | ALDH1A1 (1.00) | — | |
| SCHEMBL8192474 | 1.00 | ALDH1A1 (1.00) | — | |
| SCHEMBL10826512 | 1.00 | ALDH1A1 (1.00) | — | |
| SCHEMBL12977794 | 1.00 | ALDH1A1 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589221-B2 | Industrial scale process; treats neurodegenerative diseases; high optical purity; less dangerous reaction | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-09-15 | — | — | US | claimed |
| US-20060135802-A1 | Process for producing (2r)-2-propyloctanoic acid and intermediate therefor | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-22 | — | — | US | claimed |
| JP-1275541-A | — | — | None | — | — | JP | disclosed |
| JP-63243058-A | — | — | None | — | — | JP | disclosed |
| CN-116042742-A | Synthesis method | 葛兰素史克知识产权第二有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-111471662-B | SlEH1 mutant and application thereof in enantiotropic hydrolyzed epoxides | 江南大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-111471662-A | SlEH1 mutant and application thereof in enantiotropic hydrolyzed epoxides | 江南大学 | 2020-07-31 | — | — | CN | disclosed |
| CN-109486866-A | The method that biocatalysis prepares (S) -4- decyl alcohol | 上海合全药业股份有限公司 | 2019-03-19 | — | — | CN | disclosed |
| CN-109415329-A | Synthesis method | 葛兰素史克知识产权第二有限公司 | 2019-03-01 | — | — | CN | disclosed |
| US-20170204075-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-07-20 | — | — | US | disclosed |
| US-20170204075-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-07-20 | — | — | US | disclosed |
| US-4963288-A | Fluoroalkoxydiphenyl pyrimidine, liquid crystal composition and electro-optic element | CHISSO CORPORATION (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0357739-A1 | CHIRAL DERIVATIVES OF 1,2-DIFLUOROBENZENE | MERCK PATENT GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |
| JP-H01275541-A | PRODUCTION OF 4-ALKANOLS HAVING OPTICAL ACTIVITY | NIPPON MINING CO LTD | 1989-11-06 | — | — | JP | disclosed |
| US-4873018-A | 2-FLUORO-1-ALKANOL DERIVATIVES HAVING A RELEASABLE SUBSTITUENT; INCREASED SPONTANEOUS POLARIZATION; STABILITY | CANON KABUSHIKI KAISHA (JP) | 1989-10-10 | — | — | US | disclosed |
| WO-1989008639-A1 | CHIRAL DERIVATIVES OF 1,2-DIFLUOROBENZENE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |
| EP-0332025-A1 | Chiral derivatives of 1,2-difluorobenzenes | MERCK PATENT GmbH (DE) | 1989-09-13 | — | — | EP | disclosed |
| US-4798680-A | 2-FLUORO-1-ALKANOL | CANON KABUSHIKI KAISHA (JP) | 1989-01-17 | — | — | US | disclosed |
| JP-S63243058-A | PRODUCTION OF OPTICALLY ACTIVE ALPHA-METHYLALKYLCARBOXYLIC ACID | NIPPON MINING CO LTD | 1988-10-07 | — | — | JP | disclosed |
| EP-0278665-A2 | 2-Substituted-alkyl ether and liquid crystal composition | Chisso Corporation (JP) | 1988-08-17 | — | — | EP | disclosed |