SCHEMBL26185697

SCHEMBL26185697

Nc1cccc(C(c2cccc(N)c2)C(c2cccc(N)c2)c2cccc(N)c2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.58
CASP1 P29466 1/20 0.58
RECQL P46063 1/20 0.58
CPN1 P15169 1/20 0.47
CPB2 Q96IY4 1/20 0.47
ALDH1A1 P00352 5/20 0.46
KDM4E B2RXH2 2/20 0.46
ENPP2 Q13822 1/20 0.46
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
CA9 Q16790 3/20 0.46
CA12 O43570 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
CA14 Q9ULX7 2/20 0.46
CA7 P43166 1/20 0.46
MAOA P21397 4/20 0.44
LMNA P02545 2/20 0.41
TSHR P16473 2/20 0.41
MAPK1 P28482 1/20 0.41
MAOB P27338 4/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9804160 0.91 CYP3A4 (0.48) CYP3A4CASP1RECQLCPN1CPB2
SCHEMBL17508795 0.91 CYP3A4 (0.48) CYP3A4CASP1RECQLCPN1CPB2
SCHEMBL4073301 0.86 CA1 (0.58) CYP3A4CASP1RECQLCPN1CPB2
SCHEMBL16424114 0.83 CYP3A4 (0.58) CYP3A4CASP1RECQLCPN1CPB2
SCHEMBL17463865 0.81 CYP3A4 (0.55) CYP3A4CASP1RECQLCPN1CPB2
SCHEMBL29237064 0.81 CYP3A4 (0.55) CYP3A4CASP1RECQLCPN1CPB2
SCHEMBL17064637 0.80 CA1 (0.57) CYP3A4CASP1RECQLCPN1CPB2
SCHEMBL17468939 0.79 CYP3A4 (0.52) CYP3A4CASP1RECQLCPN1CPB2
SCHEMBL11617211 0.79 CYP3A4 (0.52) CYP3A4CASP1RECQLCPN1CPB2
SCHEMBL272384 0.79 CYP3A4 (0.52) CYP3A4CASP1RECQLCPN1CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331927-A1 POLYMETALLOXANE-CONTAINING COMPOSITION, CURED BODY, MEMBER, ELECTRONIC COMPONENT, AND FIBER TORAY INDUSTRIES, INC. (JP) 2023-10-19 US disclosed