SCHEMBL26186643

SCHEMBL26186643

O=C(C1=CCCC=C1)c1ccc(C(=O)c2ccc(C(=O)c3ccc(Oc4ccccc4)cc3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 6/20 0.57
PARP10 Q53GL7 1/20 0.46
POLB P06746 1/20 0.46
ELANE P08246 2/20 0.45
ACACB O00763 1/20 0.44
ACACA Q13085 1/20 0.44
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
ALOX12 P18054 1/20 0.42
BCL2 P10415 2/20 0.42
MCL1 Q07820 2/20 0.42
ERCC5 P28715 1/20 0.41
FEN1 P39748 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26624250 0.82 ELANE (0.43) SRD5A2POLBELANEALDH1A1
SCHEMBL18869776 0.81 SMN1; SMN2 (0.47) POLBALDH1A1
SCHEMBL13943432 0.80 MAPT (0.49) PARP10ALDH1A1
SCHEMBL2866068 0.79 SRD5A2 (0.88) SRD5A2PARP10POLBELANEALDH1A1
SCHEMBL13599782 0.79 SRD5A2 (0.88) SRD5A2PARP10POLBELANEALDH1A1
SCHEMBL235530 0.79 SRD5A2 (0.88) SRD5A2PARP10POLBELANEALDH1A1
SCHEMBL1082112 0.79 SRD5A2 (0.88) SRD5A2PARP10POLBELANEALDH1A1
SCHEMBL9536469 0.79 SRD5A2 (0.88) SRD5A2PARP10POLBELANEALDH1A1
SCHEMBL22415445 0.77 SRD5A2 (0.84) SRD5A2PARP10POLBELANEALDH1A1
SCHEMBL234249 0.77 SRD5A2 (0.84) SRD5A2PARP10POLBELANEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4206176-A1 METHOD FOR PREPARING 1,4-BIS(4-PHENOXYBENZOYL)BENZENE AND 1,4-BIS(4-PHENOXYBENZOYL)BENZENE PREPARED THEREBY Hanwha Solutions Corporation (KR) 2023-07-05 EP disclosed