Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | IL1B | P01584 | 2/20 | 0.33 |
| ▸ | HTR3A | P46098 | 3/20 | 0.32 |
| ▸ | TYK2 | P29597 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL263753 | 0.91 | MEN1 (0.47) | MEN1KMT2AGAAFOXO1KDM4E | |
| SCHEMBL4174142 | 0.84 | MEN1 (0.46) | MEN1KMT2AGAAKDM4CFOXO1 | |
| SCHEMBL4587943 | 0.83 | MEN1 (0.45) | MEN1KMT2AGAAKDM4CFOXO1 | |
| Oxalic Acid SCHEMBL4588543 | 0.81 | MEN1 (0.43) | MEN1KMT2AGAAKDM4CFOXO1 | |
| Trifluoroacetic Acid SCHEMBL261518 | 0.81 | MEN1 (0.44) | MEN1KMT2AGAAKDM4CFOXO1 | |
| SCHEMBL262831 | 0.80 | MEN1 (0.47) | MEN1KMT2AGAAFOXO1KDM4E | |
| SCHEMBL263468 | 0.80 | MEN1 (0.44) | MEN1KMT2AGAAKDM4CFOXO1 | |
| Oxalic Acid SCHEMBL262151 | 0.79 | MEN1 (0.43) | MEN1KMT2AGAAKDM4CFOXO1 | |
| SCHEMBL4588550 | 0.78 | MEN1 (0.42) | MEN1KMT2AGAAKDM4CFOXO1 | |
| SCHEMBL632342 | 0.78 | MEN1 (0.44) | MEN1KMT2AGAAKDM4CFOXO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120136025-A1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2012-05-31 | — | — | US | disclosed |
| US-8133882-B2 | Quinolone derivative or pharmaceutically acceptable salt thereof | ASTELLAS PHARMA INC (JP) | 2012-03-13 | — | — | US | disclosed |
| EP-1995240-B1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2012-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136025-A1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | P2RY10, P2RY12, P2RY11 | MEN1 3327/4885KMT2A 2966/4885GAA 4203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.