Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.34 |
| ▸ | IL1B | P01584 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.32 |
| ▸ | GLP1R | P43220 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL4588543 | 0.98 | MEN1 (0.43) | MEN1GAAKMT2AFOXO1KDM4C | |
| Trifluoroacetic Acid SCHEMBL261518 | 0.96 | MEN1 (0.44) | MEN1GAAKMT2AFOXO1KDM4C | |
| SCHEMBL4588550 | 0.90 | MEN1 (0.42) | MEN1GAAKMT2AFOXO1KDM4C | |
| SCHEMBL4174142 | 0.90 | MEN1 (0.46) | MEN1GAAKMT2AFOXO1KDM4C | |
| Hydrochloric Acid SCHEMBL4588096 | 0.89 | MEN1 (0.48) | MEN1GAAKMT2AFOXO1KDM4E | |
| SCHEMBL632342 | 0.88 | MEN1 (0.44) | MEN1GAAKMT2AFOXO1KDM4C | |
| SCHEMBL263468 | 0.85 | MEN1 (0.44) | MEN1GAAKMT2AFOXO1KDM4C | |
| Oxalic Acid SCHEMBL262151 | 0.84 | MEN1 (0.43) | MEN1GAAKMT2AFOXO1KDM4C | |
| SCHEMBL261879 | 0.83 | MEN1 (0.43) | MEN1GAAKMT2AFOXO1KDM4C | |
| SCHEMBL4586175 | 0.81 | MEN1 (0.64) | MEN1GAAKMT2AFOXO1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1995240-A1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Astellas Pharma Inc. (JP) | 2008-11-26 | — | — | EP | disclosed |