SCHEMBL261889

SCHEMBL261889

c1ccc2c(c1)c1cnccc1n2-c1ccc(Cc2ccc(-n3c4ccccc4c4ccncc43)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.49
MAOB P27338 4/20 0.49
ACHE P22303 2/20 0.49
KDM4E B2RXH2 1/20 0.43
ATM Q13315 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CYP2D6 P10635 1/20 0.43
REN P00797 2/20 0.40
HDAC2 Q92769 2/20 0.40
HDAC6 Q9UBN7 2/20 0.40
HDAC3 O15379 1/20 0.40
CDK4 P11802 1/20 0.39
CDK6 Q00534 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
PTPN1 P18031 1/20 0.38
KCNH2 Q12809 1/20 0.38
IDO1 P14902 1/20 0.36
AOC2 O75106 1/20 0.36
DDB1 Q16531 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15280902 0.96 MAOA (0.46) MAOAMAOBACHEKDM4EATM
SCHEMBL261510 0.96 MAOA (0.53) MAOAMAOBACHEKDM4EATM
SCHEMBL261890 0.96 KDM4E (0.47) MAOAMAOBACHEKDM4EATM
SCHEMBL262041 0.96 MAOA (0.53) MAOAMAOBACHEKDM4EATM
SCHEMBL261874 0.96 MAOA (0.53) MAOAMAOBACHEKDM4EATM
SCHEMBL261507 0.96 MAOA (0.53) MAOAMAOBACHEKDM4EATM
SCHEMBL4570441 0.96 KDM4E (0.47) MAOAMAOBACHEKDM4EATM
SCHEMBL261840 0.91 MAOA (0.49) MAOAMAOBACHEKDM4EATM
SCHEMBL261524 0.91 MAOA (0.49) MAOAMAOBACHEKDM4EATM
SCHEMBL262071 0.91 MAOA (0.49) MAOAMAOBACHEKDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8133597-B2 Organic electroluminescent device, display and illuminating device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-03-13 US disclosed
US-8133597-B2 Organic electroluminescent device, display and illuminating device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-03-13 US disclosed
US-20090160318-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-06-25 US disclosed
US-20090160318-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-06-25 US disclosed
US-20080088230-A1 Organic electroluminescent element and display KONICA MINOLTA HOLDINGS, INC. (JP) 2008-04-17 US disclosed
US-20080088230-A1 Organic electroluminescent element and display KONICA MINOLTA HOLDINGS, INC. (JP) 2008-04-17 US disclosed