Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.36 |
| ▸ | ESRRG | P62508 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23879572 | 0.84 | MCL1 (0.44) | KMT2ANPC1RAB9AMCL1ALDH1A1 | |
| SCHEMBL23879637 | 0.81 | MCL1 (0.42) | KMT2ANPC1RAB9AMCL1ALDH1A1 | |
| SCHEMBL26189496 | 0.80 | MAPT (0.39) | KMT2ANPC1RAB9AMCL1ALDH1A1 | |
| SCHEMBL24268121 | 0.78 | MCL1 (0.40) | KMT2ANPC1RAB9AMCL1 | |
| SCHEMBL23879530 | 0.78 | ACLY (0.52) | KMT2AMCL1MEN1GAA | |
| SCHEMBL24268128 | 0.77 | KDM1A (0.49) | MCL1GAA | |
| SCHEMBL24268165 | 0.77 | KDM1A (0.51) | KMT2AMCL1ALDH1A1MEN1GAA | |
| SCHEMBL23879629 | 0.76 | KDM1A (0.50) | MCL1 | |
| SCHEMBL23879571 | 0.76 | KDM1A (0.50) | MCL1 | |
| SCHEMBL24268146 | 0.76 | KDM1A (0.48) | MCL1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3796975-B1 | SULFONYLAMINOBENZAMIDE DERIVATIVES | ORSOBIO INC (US) | 2023-08-30 | — | — | EP | disclosed |