SCHEMBL261917

SCHEMBL261917

OC1CCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7480554 1.00
Hydrochloric Acid SCHEMBL641996 0.96
Methane SCHEMBL8125715 0.96
SCHEMBL1782968 0.78 LMNA (0.39)
SCHEMBL18373383 0.76
SCHEMBL7675924 0.73
SCHEMBL11267181 0.73
SCHEMBL8175349 0.73
SCHEMBL28254290 0.73
SCHEMBL2841282 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4143169-B1 PROCESSES FOR THE PREPARATION OF A KINASE INHIBITOR EXELIXIS INC (US) 2026-04-15 EP claimed
CN-119143648-A Azetidine trichloroacetimidate and preparation method and application thereof 中国科学技术大学 2024-12-17 CN claimed
US-20230192619-A1 Processes for the Preparation of a Kinase Inhibitor EXELIXIS, INC. 2023-06-22 US claimed
EP-4143169-A1 PROCESSES FOR THE PREPARATION OF A KINASE INHIBITOR Exelixis, Inc. (US) 2023-03-08 EP claimed
CN-115461328-A Process for preparing kinase inhibitors 埃克塞里艾克西斯公司 2022-12-09 CN claimed
CN-114892450-A Tear-resistant hydrophobic packaging paper and manufacturing method thereof 南通德润包装制品有限公司 2022-08-12 CN claimed
WO-2021222673-A1 PROCESSES FOR THE PREPARATION OF A KINASE INHIBITOR EXELIXIS, INC. (US) 2021-11-04 WO claimed
EP-3810777-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF NEUROLOGICAL DISORDERS Yumanity Therapeutics, Inc. (US) 2021-04-28 EP claimed
EP-2207876-B1 STEREO-SPECIFIC HYDROXYLATION UNIV BONN (DE) 2015-08-26 EP claimed
EP-2229355-B1 METHOD FOR PREPARING AZETIDINE DERIVATIVES SANOFI SA (FR) 2012-09-19 EP claimed
US-5349006-A Esters for coatings PPG INDUSTRIES, INC. (US) 1994-09-20 US claimed
US-5324789-A Grind vehicle for pigment grind compositions PPG INDUSTRIES, INC. (US) 1994-06-28 US claimed
WO-1993013063-A1 POLYAZETIDINOL CONTAINING MATERIALS PPG INDUSTRIES, INC. (US) 1993-07-08 WO claimed
WO-1993013142-A1 AZETIDINOL REACTION PRODUCTS PPG INDUSTRIES, INC. (US) 1993-07-08 WO claimed
EP-0161722-B1 PREPARATION OF 1-SUBSTITUTED AZETIDINE-3-OL DERIVATIVES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-04-04 EP claimed
EP-0073011-B1 1-ARYLOXY-3-ALKINYL-AMINO-2-PROPANOLS AND A METHOD FOR THEIR PREPARATION BOEHRINGER INGELHEIM KG (DE) 1986-04-02 EP claimed
EP-0073016-B1 1-ARYLOXY-3-ALKYLAMINO-2-PROPANOLS AND PROCESSES FOR THEIR PREPARATION BOEHRINGER INGELHEIM KG (DE) 1985-11-27 EP claimed
EP-0035734-B1 1-(ACYLAMINO-ARYLOXY-)2-HYDROXY-3-ALKINYL-AMINO PROPANES AND PROCESSES FOR THEIR MANUFACTURE C.H. BOEHRINGER SOHN (DE) 1983-09-21 EP claimed
EP-0035733-B1 1-(ACYLAMINO-ARYLOXY-)2-HYDROXY-3-ALKINYL-AMINO PROPANES AND PROCESSES FOR THEIR MANUFACTURE C.H. BOEHRINGER SOHN (DE) 1983-09-14 EP claimed
US-4360464-A Process for production of 1-aryloxy-aminopropane derivatives TEIKOKU HORMONE MFG. CO. LTD. (JP) 1982-11-23 US claimed