Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EYA2 | O00167 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24864279 | 0.96 | TDP1 (0.37) | KMT2AATMKDM4ETDP1ALDH1A1 | |
| SCHEMBL20756674 | 0.89 | KMT2A (0.42) | KMT2AATMKDM4ETDP1ALDH1A1 | |
| Edetol SCHEMBL2803498 | 0.81 | TSHR (0.39) | KMT2AATMKDM4ETDP1ALDH1A1 | |
| Edetol SCHEMBL48412 | 0.81 | TSHR (0.39) | KMT2AATMKDM4ETDP1ALDH1A1 | |
| SCHEMBL11126380 | 0.80 | TDP1 (0.56) | KMT2AATMKDM4ETDP1EYA2 | |
| SCHEMBL5618680 | 0.78 | TDP1 (0.61) | KMT2AATMKDM4ETDP1EYA2 | |
| Edetol SCHEMBL5596270 | 0.78 | TDP1 (0.61) | KMT2AATMKDM4ETDP1EYA2 | |
| SCHEMBL6260966 | 0.78 | KDM4E (0.38) | KMT2AATMKDM4ETDP1ALDH1A1 | |
| Edetol SCHEMBL20942798 | 0.78 | KDM4E (0.38) | KMT2AATMKDM4ETDP1ALDH1A1 | |
| Edetol SCHEMBL8989695 | 0.78 | KDM4E (0.38) | KMT2AATMKDM4ETDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163313-B2 | Compositions containing amines and use thereof | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2012-04-24 | — | — | US | disclosed |
| US-8163313-B2 | Compositions containing amines and use thereof | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2012-04-24 | — | — | US | disclosed |