Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26199422 | 1.00 | ALDH1A1 (0.32) | ALDH1A1LMNAHSD17B10CYP2C9HTT | |
| SCHEMBL26199421 | 1.00 | ALDH1A1 (0.32) | ALDH1A1LMNAHSD17B10CYP2C9HTT | |
| SCHEMBL26199487 | 1.00 | ALDH1A1 (0.32) | ALDH1A1LMNAHSD17B10CYP2C9HTT | |
| SCHEMBL26199486 | 0.83 | ALDH1A1 (0.36) | ALDH1A1LMNAHSD17B10CYP2C9HTT | |
| SCHEMBL26199418 | 0.83 | ALDH1A1 (0.36) | ALDH1A1LMNAHSD17B10CYP2C9HTT | |
| SCHEMBL26199420 | 0.83 | ALDH1A1 (0.36) | ALDH1A1LMNAHSD17B10CYP2C9HTT | |
| SCHEMBL26199488 | 0.83 | ALDH1A1 (0.36) | ALDH1A1LMNAHSD17B10CYP2C9HTT | |
| SCHEMBL26199183 | 0.79 | MGAM (0.34) | ALDH1A1LMNAHSD17B10HTTALOX15 | |
| SCHEMBL26199255 | 0.79 | MGAM (0.34) | ALDH1A1LMNAHSD17B10HTTALOX15 | |
| SCHEMBL19945234 | 0.78 | ALDH1A1 (0.34) | ALDH1A1LMNAHSD17B10HTTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130008-A2 | PHARMACEUTICAL COMPOSITIONS OF 6-(2-(2H-TETRAZOL-5-YL)ETHYL)DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AND DERIVATIVES THEREOF | SEA PHARMACEUTICALS LLC (US) | 2023-07-06 | — | — | WO | disclosed |