SCHEMBL26201228

SCHEMBL26201228

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cccc5c4sc4nc6ccccc6n45)cc3)n2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.43
HSD17B10 Q99714 6/20 0.43
ALDH1A1 P00352 6/20 0.38
MEN1 O00255 6/20 0.38
KMT2A Q03164 6/20 0.38
MAPT P10636 6/20 0.38
POLB P06746 5/20 0.38
DUSP3 P51452 2/20 0.38
RECQL P46063 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
USP2 O75604 2/20 0.38
APAF1 O14727 1/20 0.38
APEX1 P27695 1/20 0.38
MCL1 Q07820 1/20 0.38
PTPN7 P35236 1/20 0.38
HPGD P15428 5/20 0.37
SMN1; SMN2 Q16637 5/20 0.37
NPC1 O15118 4/20 0.37
RAB9A P51151 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26204964 0.93 HSD17B10 (0.43) KDM4EHSD17B10ALDH1A1MEN1KMT2A
SCHEMBL16441889 0.93 KDM4E (0.46) KDM4EHSD17B10ALDH1A1MEN1KMT2A
SCHEMBL16441890 0.93 KDM4E (0.48) KDM4EHSD17B10ALDH1A1MEN1KMT2A
SCHEMBL26198204 0.89 KDM4E (0.37) KDM4EHSD17B10ALDH1A1MEN1KMT2A
SCHEMBL26197527 0.88 HSD17B10 (0.45) KDM4EHSD17B10ALDH1A1MEN1KMT2A
SCHEMBL26201924 0.87 HSD17B10 (0.37) KDM4EHSD17B10ALDH1A1MEN1KMT2A
SCHEMBL26198121 0.85 KDM4E (0.43) KDM4EHSD17B10ALDH1A1MEN1KMT2A
SCHEMBL16441888 0.85 KDM4E (0.43) KDM4EHSD17B10ALDH1A1MEN1KMT2A
SCHEMBL26198192 0.83 ALDH1A1 (0.36) KDM4EHSD17B10ALDH1A1MEN1KMT2A
SCHEMBL26204877 0.83 KDM4E (0.42) KDM4EHSD17B10ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230284525-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-09-07 US disclosed