SCHEMBL26201637

SCHEMBL26201637

C=CCOCC[C@@H]1[C@@H](C)OC(n2c[n+](C)c3c(=O)[nH]c(N)nc32)[C@@H]1O

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
TLR7 Q9NYK1 8/20 0.34
HINT1 P49773 3/20 0.34
KRAS P01116 1/20 0.33
GSK3A P49840 2/20 0.32
RPS6KA3 P51812 2/20 0.32
MAPK14 Q16539 2/20 0.32
NT5E P21589 1/20 0.32
TGM2 P21980 1/20 0.32
PNP P00491 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26201881 0.90 HINT1 (0.37) TLR7HINT1GSK3ARPS6KA3MAPK14
SCHEMBL26569369 0.89 HINT1 (0.37) TLR7HINT1GSK3ARPS6KA3MAPK14
SCHEMBL26201989 0.88 TLR7 (0.36) TLR7HINT1KRASGSK3ARPS6KA3
SCHEMBL26201631 0.88 TLR7 (0.38) TLR7HINT1KRASGSK3ARPS6KA3
SCHEMBL26202558 0.88 TLR7 (0.38) TLR7HINT1KRASGSK3ARPS6KA3
SCHEMBL26569371 0.87 HINT1 (0.36) TLR7HINT1GSK3ARPS6KA3MAPK14
SCHEMBL26201432 0.87 TLR7 (0.36) TLR7HINT1GSK3ARPS6KA3MAPK14
SCHEMBL26201971 0.85 TLR7 (0.38) TLR7HINT1GSK3ARPS6KA3MAPK14
SCHEMBL26569031 0.85 TLR7 (0.37) TLR7HINT1GSK3ARPS6KA3MAPK14
SCHEMBL26568527 0.85 PNP (0.40) MEN1KMT2ATLR7HINT1GSK3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023159930-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND 广州市恒诺康医药科技有限公司 2023-08-31 WO disclosed