SCHEMBL26201639

SCHEMBL26201639

CO[C@@H]1[C@H](OP(=O)(O)OC[C@H]2O[C@@H](n3cnc4c(=O)[nH]c(N)nc43)[C@H](O)[C@@H]2O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O[C@H]1n1cnc2c(N)ncnc21

nearest known ligand 0.73

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RNASEL Q05823 9/20 0.73
P2RY1 P47900 3/20 0.65
P2RY2 P41231 2/20 0.65
SRC P12931 1/20 0.65
P2RX1 P51575 1/20 0.65
P2RX3 P56373 1/20 0.65
P2RX4 Q99571 1/20 0.65
P2RX2 Q9UBL9 1/20 0.65
ALDH1A1 P00352 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
TGM2 P21980 1/20 0.62
FUT5 Q11128 1/20 0.62
MACROD2 A1Z1Q3 1/20 0.61
SIRT6 Q8N6T7 1/20 0.61
MACROD1 Q9BQ69 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26201887 1.00 RNASEL (0.73) RNASELP2RY1P2RY2SRCP2RX1
SCHEMBL26578079 1.00 RNASEL (0.73) RNASELP2RY1P2RY2SRCP2RX1
SCHEMBL26577103 1.00 RNASEL (0.73) RNASELP2RY1P2RY2SRCP2RX1
SCHEMBL24941695 0.99 RNASEL (0.72) RNASELP2RY1P2RY2SRCP2RX1
SCHEMBL26067694 0.99 RNASEL (0.72) RNASELP2RY1P2RY2SRCP2RX1
SCHEMBL26209310 0.99 RNASEL (0.72) RNASELP2RY1P2RY2SRCP2RX1
SCHEMBL26202439 0.97 RNASEL (0.70) RNASELP2RY1P2RX1P2RX3P2RX2
SCHEMBL21450697 0.96 RNASEL (0.67) RNASELP2RY1P2RY2SRCP2RX1
SCHEMBL26202708 0.95 RNASEL (0.65) RNASELP2RY1P2RY2SRCP2RX1
SCHEMBL26067576 0.95 RNASEL (0.65) RNASELP2RY1P2RY2SRCP2RX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4261217-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND Guangzhou Henovcom Bioscience Co., Ltd. (CN) 2023-10-18 EP disclosed
WO-2023159930-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND 广州市恒诺康医药科技有限公司 2023-08-31 WO disclosed