SCHEMBL26202039

SCHEMBL26202039

NCCc1c[nH]c2c(Br)cc(O)c(F)c12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 5/20 0.44
MPO P05164 2/20 0.44
SLC6A4 P31645 1/20 0.44
HTR2C P28335 3/20 0.43
RECQL P46063 3/20 0.40
MEN1 O00255 2/20 0.40
RAD52 P43351 2/20 0.40
KMT2A Q03164 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
GAPDH P04406 1/20 0.40
THRB P10828 1/20 0.40
APEX1 P27695 1/20 0.40
BLM P54132 1/20 0.40
HTR1A P08908 2/20 0.39
NEK1 Q96PY6 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.39
ALOX15 P16050 1/20 0.39
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5347326 0.74 HTR2A (0.47) HTR2AMPOSLC6A4HTR2CKMT2A
SCHEMBL2533034 0.74 HTR2A (0.50) HTR2AMPOSLC6A4HTR2CKMT2A
Hydrochloric Acid SCHEMBL21546048 0.73 HTR2A (0.49) HTR2AMPOSLC6A4HTR2CKMT2A
SCHEMBL30712091 0.72 HTR1A (0.68) HTR2AMPOSLC6A4HTR2CRECQL
SCHEMBL31742617 0.69 HTR2C (0.60) HTR2AMPOSLC6A4HTR2CRECQL
SCHEMBL25381818 0.68 HTR1A (0.67) HTR2AMPOHTR2CRECQLMEN1
SCHEMBL25381712 0.68 HTR2C (0.58) HTR2AMPOHTR2CRECQLHTR1A
SCHEMBL2537704 0.67 HTR2A (0.59) HTR2AMPOSLC6A4HTR2CKMT2A
SCHEMBL31730633 0.67 HTR2A (0.59) HTR2AMPOSLC6A4HTR2CKMT2A
SCHEMBL9407213 0.67 HTR2A (0.57) HTR2AMPOSLC6A4HTR2CRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230270768-A1 MULTI-SUBSTITUENT PSILOCYBIN DERIVATIVES AND METHODS OF USING Enveric Biosciences Canada Inc. (CA) 2023-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230270768-A1 MULTI-SUBSTITUENT PSILOCYBIN DERIVATIVES AND METHODS OF USING CNR2, CNR1, HTR1B HTR2A 11/4885MPO 4377/4885SLC6A4 54/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.