SCHEMBL26202070

SCHEMBL26202070

COC[C@H]1[C@@H](O)[C@H](n2c[n+](C)c3c(=O)[nH]c(N)nc32)O[C@@H]1C

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HINT1 P49773 5/20 0.39
TLR7 Q9NYK1 3/20 0.37
NT5E P21589 1/20 0.37
GSK3A P49840 2/20 0.37
RPS6KA3 P51812 2/20 0.37
MAPK14 Q16539 2/20 0.37
TGM2 P21980 1/20 0.35
FUT5 Q11128 1/20 0.35
PNP P00491 2/20 0.34
ADORA3 P0DMS8 1/20 0.34
EIF4E P06730 1/20 0.34
TYMS P04818 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26571022 1.00 HINT1 (0.39) HINT1TLR7NT5EGSK3ARPS6KA3
SCHEMBL26566855 1.00 HINT1 (0.39) HINT1TLR7NT5EGSK3ARPS6KA3
SCHEMBL26213741 0.92 HINT1 (0.37) HINT1TLR7NT5EGSK3ARPS6KA3
SCHEMBL26202558 0.91 TLR7 (0.38) HINT1TLR7NT5EGSK3ARPS6KA3
SCHEMBL26201631 0.91 TLR7 (0.38) HINT1TLR7NT5EGSK3ARPS6KA3
SCHEMBL26568603 0.91 HINT1 (0.40) HINT1TLR7NT5EGSK3ARPS6KA3
SCHEMBL26568857 0.90 TLR7 (0.38) HINT1TLR7NT5EGSK3ARPS6KA3
SCHEMBL26568527 0.89 PNP (0.40) HINT1TLR7NT5EGSK3ARPS6KA3
SCHEMBL26568971 0.89 HINT1 (0.39) HINT1TLR7NT5EGSK3ARPS6KA3
SCHEMBL26218377 0.89 TLR7 (0.34) HINT1TLR7NT5EGSK3ARPS6KA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4261217-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND Guangzhou Henovcom Bioscience Co., Ltd. (CN) 2023-10-18 EP disclosed
WO-2023159930-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND 广州市恒诺康医药科技有限公司 2023-08-31 WO disclosed