SCHEMBL26205964

SCHEMBL26205964

Cc1cc(C#CCCCC(=O)O)cc(OC[C@@H](C)CCC(N)=O)c1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ FFAR1 O14842 2/20 0.34
▸ CSF3R Q99062 1/20 0.33
▸ FFAR4 Q5NUL3 1/20 0.32
▸ MMP2 P08253 1/20 0.32
▸ MMP12 P39900 1/20 0.32
▸ ITGB1 P05556 1/20 0.32
▸ ITGA4 P13612 1/20 0.32
▸ GPR88 Q9GZN0 1/20 0.31
▸ FOS P01100 1/20 0.31
▸ JUN P05412 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ MCL1 Q07820 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26205967 0.90 LTB4R (0.33) FFAR1CSF3RFFAR4MMP2MMP12
SCHEMBL26205926 0.87 FFAR1 (0.42) FFAR1FFAR4MMP2MMP12ITGB1
SCHEMBL26205927 0.86 FFAR1 (0.40) FFAR1FOSJUN
SCHEMBL22525467 0.82 ITGB1 (0.36) ITGB1ITGA4
SCHEMBL26205965 0.82 TSHR (0.43) FFAR1FFAR4MMP2MMP12ITGB1
SCHEMBL26205963 0.81 TSHR (0.34) FFAR1CSF3RFFAR4GPR88FOS
SCHEMBL26205951 0.80 ITGB1 (0.34) ITGB1ITGA4L3MBTL1
SCHEMBL26205958 0.79 LTB4R (0.38) FFAR1FFAR4MMP2MMP12ITGB1
SCHEMBL26205966 0.78 FFAR4 (0.37) FFAR1CSF3RFFAR4GPR88FOS
SCHEMBL26206480 0.77 FFAR4 (0.39) FFAR1CSF3RFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11746120-B2 Stat degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2023-09-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11746120-B2 Stat degraders and uses thereof STAT4, STAT1, STAT3 FFAR1 4114/4885CSF3R 1132/4885FFAR4 3503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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